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A sensitive radioenzymatic assay for norepinephrine in tissues and plasma

Life SciencesPublished 1 February 1975
David P. Henry, Barbra J. Starman, David G. Johnson, Robert H. Williams
Citations475
SJR quartileQ1
SJR score1.31
SNIP1.07

TL;DR

A procedure for measuring picogram quantities of norepinephrine has been developed utilizing partially purified bovine adrenal phenylethanolamine-N-methyl-transferase and 3 [H]-S-adenosyl-methionine, applicable to many body tissues and fluids, including brain and plasma.

Abstract

A procedure for measuring picogram quantities of norepinephrine has been developed utilizing partially purified bovine adrenal phenylethanolamine-N-methyl-transferase and 3[H]-S-adenosyl-methionine. The sensitivity of the assay is 25 pg, and the procedure is applicable to many body tissues and fluids, including brain and plasma.

Keywords

MedicineBiochemistry, Genetics and Molecular Biology