Organokatalytische asymmetrische Dominoreaktionen: eine Kaskade aus Michael‐Addition und Aldehyd‐α‐Alkylierung
Angewandte ChemiePublished 27 August 2008
Dieter Enders, Chuan Wang, Jan W. Bats
Citations106
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Abstract
Einen direkten Zugang zu cyclischen γ-Nitroaldehyden mit einem vollständig aus Kohlenstoffatomen bestehenden, quartären Stereozentrum eröffnet eine neue organokatalytische diastereo- und enantioselektive Kaskade aus Michael-Addition und Aldehyd-α-Alkylierung (siehe Schema). Die entsprechenden γ-Aminosäuren sind in zwei Stufen zugänglich.
Keywords
ChemistryBiochemistry, Genetics and Molecular Biology
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