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Low-Dose Repeated Caffeine Administration for Circadian-Phase-Dependent Performance Degradation During Extended Wakefulness

SLEEPPublished 1 May 2004
James K. Wyatt, Christian Cajochen, Angela Ritz-De Cecco, Charles A. Czeisler, Derk‐Jan Dijk
Citations181
SJR quartileQ1
SJR score1.80
SNIP1.63

TL;DR

High-frequency low-dose caffeine administration is effective in countering the detrimental performance effects of extended wakefulness and may lead to new strategies to use caffeine in situations in which neurobehavioral functioning is affected by sleep loss.

Abstract

High-frequency low-dose caffeine administration is effective in countering the detrimental performance effects of extended wakefulness. These data are in accordance with the hypothesis that adenosine is a mediator of performance decrements associated with extended wakefulness and may lead to new strategies to use caffeine in situations in which neurobehavioral functioning is affected by sleep loss.

Keywords

PsychologyNeuroscience