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AIDS-associated Kaposi's sarcoma: a molecular model for its pathogenesis.

PubMedPublished 1 November 1989
Barbara Ensoli, Salahuddin Sz, Gallo Rc
Citations38

TL;DR

The potential roles of specific cytokines and the virally encoded tat product in inducing Kaposi's sarcoma are considered.

Abstract

Kaposi's sarcoma is a mesenchymal tumor that is frequently observed in AIDS patients. Although the tumor is clearly associated with HIV-1 infection, little is known about the molecular events underlying its pathogenesis. Here we consider the potential roles of specific cytokines and the virally encoded tat product in inducing the tumor.

Keywords

Medicine