The tissue distribution of fructose-2,6-P2 and fructose-6-P,2-kinase in rats and the effect of starvation diabetes and hypoglycemia on hepatic fructose-2,6-P2 and fructose-6-P,2-kinase
Biochemical and Biophysical Research CommunicationsPublished 1 January 1982
Masamichi Kuwajima, Kosaku Uyeda
Citations60
SJR quartileQ2
SJR score0.75
SNIP0.56
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TL;DR
The highest concentration of fructose-2,6-P2 was found in liver, followed by brain, heart muscle, kidney, testis and skeletal muscle in decreasing order, and similar results were obtained with fructose- 6-P,2-kinase activities in these tissues.
Abstract
The tissue distribution of fructose-2,6-P2 and fructose-6-P,2-kinase in rats was determined. The highest concentration of fructose-2,6-P2 was found in liver, followed by brain, heart muscle, kidney, testis and skeletal muscle in decreasing order. Similar results were obtained with fructose-6-P,2-kinase activities in these tissues. Starvation, streptozotocin-induced diabetes or hypoglycemia lowers the fructose-2,6-P2 levels and fructose-6-P,2-kinase activity in the liver.
Keywords
MedicineBiochemistry, Genetics and Molecular Biology
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