Transcriptome of Enterohemorrhagic <i>Escherichia coli</i> O157 Adhering to Eukaryotic Plasma Membranes
Infection and ImmunityPublished 21 August 2004Open access
Sivan Dahan, Stuart Knutton, Robert K. Shaw, Valérie F. Crepin, Gordon Dougan, Gad Frankel
Citations77
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TL;DR
Using a DNA microarray, changes in enterohemorrhagic Escherichia coli O157:H7 gene expression during binding to plasma membranes are determined and levels of stress-associated mRNAs and mRNA encoding proteins involved in translation and type III secretion are decreased.
Abstract
Using a DNA microarray, we determined changes in enterohemorrhagic Escherichia coli O157:H7 gene expression during binding to plasma membranes. Analysis of the complete transcriptomes of the bound bacteria revealed increased levels of stress-associated mRNAs and decreased levels of mRNA encoding proteins involved in translation and type III secretion.
Keywords
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