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The nucleotide sequence of the gene encoding the K99 subunit of enterotoxigenic<i>Escherichia coli</i>

FEMS Microbiology LettersPublished 1 May 1984
Bert Roosendaal, Wim Gaastra, F K de Graaf
Citations90
SJR quartileQ3
SJR score0.60
SNIP0.59

TL;DR

The nucleotide sequence of the gene encoding the K99 fimbrial subunit of enterotoxigenic Escherichia coli was determined and it appeared that the subunit is composed of 159 amino acid residues preceded by a N-terminal signal sequence.

Abstract

The nucleotide sequence of the gene encoding the K99 fimbrial subunit of enterotoxigenic Escherichia coli was determined. It appeared that the subunit is composed of 159 amino acid residues preceded by a N-terminal signal sequence of 22 amino acid residues. The secondary structure of the mature K99 polypeptide and the location of potential antigenic determinants were predicted. A comparison was made between the amino acid sequence of the K99 subunit and the subunits of other fimbrial adhesins.

Keywords

Biochemistry, Genetics and Molecular Biology