Diosgenin induces cell cycle arrest and apoptosis in human leukemia K562 cells with the disruption of Ca2+ homeostasis
Cancer Chemotherapy and PharmacologyPublished 14 September 2004
Mingjie Liu, Zhao Wang, Yong Ju, Ricky Ngok‐Shun Wong, Qingyu Wu
Citations181
SJR quartileQ1
SJR score0.97
SNIP0.79
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TL;DR
Diosgenin inhibits K562 cell proliferation via cell cycle G2/M arrest and apoptosis, with disruption of Ca2+ homeostasis and mitochondrial dysfunction playing vital roles.
Abstract
Diosgenin inhibits K562 cell proliferation via cell cycle G2/M arrest and apoptosis, with disruption of Ca2+ homeostasis and mitochondrial dysfunction playing vital roles.
Keywords
Biochemistry, Genetics and Molecular Biology
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