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Localization of factor-VIII-related antigen in human vascular subendothelium

BloodPublished 1 May 1980Open access
JH Rand, II Sussman, RE Gordon, SV Chu, V Solomon
Citations131
SJR quartileQ1
SJR score5.82
SNIP3.47
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TL;DR

The presence of factor-VIII-related antigen in human vascular subendothelium is demonstrated using both an immunofluorescent staining technique and electron microscopy and may have implications in the mechanism of platelet adhesion to deendothelialized blood vessel surfaces.

Abstract

Factor-VIII-related antigen has previously been shown to be synthesized by vascular endothelial cells. Using both an immunofluorescent staining technique and electron microscopy, we have demonstrated the presence of factor-VIII-related antigen in human vascular subendothelium. This finding may have implications in the mechanism of platelet adhesion to deendothelialized blood vessel surfaces.

Keywords

Medicine