Regulation of back-propagating action potentials in hippocampal neurons
Current Opinion in NeurobiologyPublished 1 June 1999
Daniel Johnston, Dax A. Hoffman, Costa M. Colbert, Jeffrey C. Magee
Citations161
SJR quartileQ1
SJR score2.54
SNIP1.27
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TL;DR
Dendritic, A-type K+ channels have been found to be modulated by protein kinases A and C and by mitogen-activated protein kinase, and the electrical signalling ability of these dendrites is highly regulated by a number of neurotransmitters and second-messenger systems.
Abstract
Protein kinase C has recently been shown to modulate the slow recovery from inactivation of Na+ channels in apical dendrites of hippocampal CA1 pyramidal neurons. Moreover, dendritic, A-type K+ channels have been found to be modulated by protein kinases A and C and by mitogen-activated protein kinase. The electrical signalling ability of these dendrites is thus highly regulated by a number of neurotransmitters and second-messenger systems.
Keywords
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