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4-Isothiocyanato-4′-nitrodiphenylamine (C9333-Go/CGP 4540) an anthelminthic with an unusual spectrum of activity against intestinal nematodes, filariae and schistosomes

Cellular and Molecular Life SciencesPublished 1 April 1976
H.P. Striebel
Citations53
SJR quartileQ1
SJR score2.30
SNIP1.48

TL;DR

4-isothiocyanato-4′-nitrodiphenylamine was found to possess activity against intestinal nematodes in mice, against schistosomes in various hosts including primates and against two filarial species in the mongolian jird.

Abstract

4-isothiocyanato-4'-nitrodiphenylamine was found to possess activity against intestinal nematodes in mice, against schistosomes in various hosts including primates and against two filarial species in the mongolian jird. Upon administration in a single oral dose it is equally effective against S. haematobium, S. mansoni and S. japonicum.

Keywords

Immunology and MicrobiologyMedicineEnvironmental Science