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Efficacy and Safety of Neuroleptics in Behavioral Disorders Associated With Dementia

The Journal of Clinical PsychiatryPublished 15 October 1998
Krista L. Lanctôt, Tamara S. Best, Nicole Mittmann, Barbara A. Liu, Paul Oh, Thomas R. Einarson
Citations137
SJR quartileQ1
SJR score1.49
SNIP1.38

TL;DR

Neuroleptics have small but significant efficacy over placebo in this population of dementia patients, and the efficacy rate is equivalent to the side effect rate.

Abstract

Neuroleptics have small but significant efficacy over placebo in this population, and the efficacy rate is equivalent to the side effect rate. Comparing different neuroleptics shows they have similar efficacy, side effects, and dropout rates. Further study to determine more specific drug-responsive behaviors is needed to maximize benefits of these drugs.

Keywords

Medicine