Risk of breast cancer among Norwegian women with visual impairment
British Journal of CancerPublished 1 January 2001Open access
J Kliukiene, Tore Tynes, A Andersen
Citations115
SJR quartileQ1
SJR score3.14
SNIP1.83
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TL;DR
These findings give support to the ‘melatonin hypothesis’ and suggest exposure to light suppresses melatonin secretion, but to a lesser degree in totally blind persons.
Abstract
Experimental studies suggest that melatonin has a protective effect against breast cancer. Exposure to light suppresses melatonin secretion, but to a lesser degree in totally blind persons. Breast cancer was investigated in a cohort of 15 412 Norwegian visually impaired women. The risk among totally blind women was 0.64 (95% CI = 0.21-1.49, 5 cases only), and for those who became blind before age of 65, the SIR was 0.51 (95% CI = 0.11-1.49). Our findings give support to the 'melatonin hypothesis'.
Keywords
Neuroscience
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