Human parietal cortex in action
Current Opinion in NeurobiologyPublished 25 March 2006
Jody C. Culham, Kenneth F. Valyear
Citations653
SJR quartileQ1
SJR score2.54
SNIP1.27
Generate an AI Snapshot to get a quick, structured summary of this paper.
Study Snapshot
ObjectiveStudy objective
MethodsResearch methodology
PopulationPopulation studied
Sample sizeSample sizes
OutcomesStudy outcomes here
ResultsStudy results comes here
LimitationsResearch study limitations comes here
A concise AI-generated summary of the paper will appear here once you click Generate AI Snapshot.
TL;DR
This work reviews the known subregions of the human posterior parietal cortex and the principles behind their organization and discusses regions of the parietal lobes specialized for particular visuomotor actions.
Abstract
Experiments using functional neuroimaging and transcranial magnetic stimulation in humans have revealed regions of the parietal lobes that are specialized for particular visuomotor actions, such as reaching, grasping and eye movements. In addition, the human parietal cortex is recruited by processing and perception of action-related information, even when no overt action occurs. Such information can include object shape and orientation, knowledge about how tools are employed and the understanding of actions made by other individuals. We review the known subregions of the human posterior parietal cortex and the principles behind their organization.
Keywords
PsychologyNeuroscience
Annual Review of NeuroscienceTHE MIRROR-NEURON SYSTEM
7,063 Citations2004Giacomo Rizzolatti, Laila Craighero
A neurophysiological mechanism appears to play a fundamental role in both action understanding and imitation, and those properties specific to the human mirror-neuron system that might explain the human capacity to learn by imitation are stressed.
Trends in NeurosciencesSeparate visual pathways for perception and action
6,550 Citations1992Melvyn A. Goodale, A. David Milner
It is proposed that the ventral stream of projections from the striate cortex to the inferotemporal cortex plays the major role in the perceptual identification of objects, while the dorsal stream projecting from the stripping to the posterior parietal region mediates the required sensorimotor transformations for visually guided actions directed at such objects.
Trends in Cognitive SciencesThe distributed human neural system for face perception
4,950 Citations2000J.V. Haxby, James V. Haxby +2 more
A model for the organization of this system that emphasizes a distinction between the representation of invariant and changeable aspects of faces is proposed and is hierarchical insofar as it is divided into a core system and an extended system.
Cognitive Brain ResearchPremotor cortex and the recognition of motor actions
4,748 Citations1996Giacomo Rizzolatti, Luciano Fadiga +2 more
It is suggested that the development of the lateral verbal communication system in man derives from a more ancient communication system based on recognition of hand and face gestures.
MIT Press eBooksAnalysis of visual behavior
4,133 Citations1982David Ingle, Melvyn A. Goodale +1 more
Analysis of Visual Behavior deals with the visual mechanisms of diverse vertebrate species from salamanders and toads to primates and humans and presents a stimulating interaction of the disciplines of anatomy, physiology, and behavioral science.
ScienceParietal Lobe: From Action Organization to Intention Understanding
2,011 Citations2005Leonardo Fogassi, Pier Francesco Ferrari +4 more
Inferior parietal lobule neurons were studied when monkeys performed motor acts embedded in different actions and when they observed similar acts done by an experimenter to allow the observer to understand the agent's intentions.
Cerebral CortexAction Observation and Acquired Motor Skills: An fMRI Study with Expert Dancers
1,973 Citations2004Beatriz Calvo‐Merino, Daniel E. Glaser +3 more
The results show that this 'mirror system' integrates observed actions of others with an individual's personal motor repertoire, and suggest that the human brain understands actions by motor simulation.
ScienceHearing Sounds, Understanding Actions: Action Representation in Mirror Neurons
1,799 Citations2002E. Kohler, Christian Keysers +4 more
This work found neurons in monkey premotor cortex that discharge when the animal performs a specific action and when it hears the related sound, and this discovery in the monkey homolog of Broca's area might shed light on the origin of language.
NatureA tension-based theory of morphogenesis and compact wiring in the central nervous system
1,694 Citations1997David C. Van Essen
Many structural features of the mammalian central nervous system can be explained by a morphogenetic mechanism that involves mechanical tension along axons, dendrites and glial processes.
NeuroImageRepresentation of Manipulable Man-Made Objects in the Dorsal Stream
1,252 Citations2000Linda L. Chao, Alex Martin
The left ventral premotor region that responded selectively to tools in the current study may be the human homolog of the monkey canonical F5 area, which responds to the visual presentation of graspable objects.
Journal of Cognitive NeuroscienceListening to Action-related Sentences Activates Fronto-parietal Motor Circuits
1,240 Citations2005Marco Tettamanti, Giovanni Buccino +8 more
The results showed that listening to action-related sentences activates a left fronto-parieto-temporal network that includes the pars opercularis of the inferior frontal gyrus (Broca's area), as well as the inferior parietal lobule, the intraparietal sulcus, and the posterior middle temporal gyrus.
Annual Review of NeuroscienceTHE HUMAN VISUAL CORTEX
1,211 Citations2004Kalanit Grill‐Spector, Rafael Malach
Recent findings and methods employed to uncover the functional properties of the human visual cortex focusing on two themes: functional specialization and hierarchical processing are reviewed.
Electroencephalography and Clinical NeurophysiologyThe organization of the cortical motor system: new concepts
1,108 Citations1998Giacomo Rizzolatti, Giuseppe Luppino +1 more
Anatomical and brain-imaging evidence suggest that the organization of human motor cortex is based on the same principles as that of the motor cortices of humans and non-human primates.
BrainOPTIC ATAXIA: A SPECIFIC DISRUPTION IN VISUOMOTOR MECHANISMS
963 Citations1988M.T. Perenin, Alain Vighetto
The findings suggest that the 2 types of visuomotor mechanisms responsible for the proximal and distal components of visually-directed arm movements are controlled by the parietal cortex and that there should exist a hemisphere asymmetry in the functional organization of these mechanisms.
NeuronNeural Circuits Underlying Imitation Learning of Hand Actions
899 Citations2004Giovanni Buccino, Stefan Vogt +5 more
The results showed that the basic circuit underlying imitation learning consists of the inferior parietal lobule and the posterior part of the superior frontal gyrus plus the adjacent premotor cortex (mirror neuron circuit), plus structures involved in motor preparation (dorsal prem motor cortex, superior parietal lobe, rostral mesial areas).
Proceedings of the National Academy of SciencesDistributed representation of objects in the human ventral visual pathway
899 Citations1999Alumit Ishai, Leslie G. Ungerleider +3 more
It is proposed that the functional architecture of the ventral visual pathway is not a mosaic of category-specific modules but instead is a continuous representation of information about object form that has a highly consistent and orderly topological arrangement.
NeuronBinocular Rivalry and Visual Awareness in Human Extrastriate Cortex
886 Citations1998Frank Tong, Ken Nakayama +2 more
Nature NeuroscienceRole of the posterior parietal cortex in updating reaching movements to a visual target
839 Citations1999Michel Desmurget, Charles M. Epstein +4 more
Transcranial magnetic stimulation was applied over the left PPC during target presentation and disrupted path corrections that normally occur in response to target jumps, but had no effect on those directed at stationary targets.
Journal of NeuroscienceFunctional Analysis of V3A and Related Areas in Human Visual Cortex
832 Citations1997Roger B. H. Tootell, Janine D. Mendola +6 more
Using functional magnetic resonance imaging (fMRI) and cortical unfolding techniques, the retinotopy, motion sensitivity, and functional organization of human area V3A was analyzed and the situation is qualitatively reversed: V3 is reported to be prominently motion-selective, whereas V 3A is less so.
Current Opinion in NeurobiologyNeuroimaging of cognitive functions in human parietal cortex
820 Citations2001Jody C. Culham, Nancy Kanwisher
Functional neuroimaging has proven highly valuable in mapping human sensory regions, particularly visual areas in occipital cortex, but the extension of human brain mapping into higher-order "association cortex" may prove to be a challenge.
NeuronPolymodal Motion Processing in Posterior Parietal and Premotor Cortex
807 Citations2001Frank Bremmer, Anja Schlack +6 more
Functional MRI in normals while presenting moving visual, tactile, or auditory stimuli revealed increased neural activity evoked by all three stimulus modalities in the depth of the intraparietal sulcus, ventral premotor, and lateral inferior postcentral cortex.
NeuronTopographical Layout of Hand, Eye, Calculation, and Language-Related Areas in the Human Parietal Lobe
769 Citations2002Olivier Simon, Jean‐François Mangin +3 more
Human homologs of the monkey areas AIP, MIP, V6A, and LIP are suggested and imply a large cortical expansion of the inferior parietal lobule correlated with the development of human language and calculation abilities.
Journal of Cognitive NeuroscienceNeural Circuits Involved in the Recognition of Actions Performed by Nonconspecifics: An fMRI Study
758 Citations2004Giovanni Buccino, Fausta Lui +6 more
Assessment of cortical areas active during the observation of mouth actions performed by humans and by individuals belonging to other species suggests that actions made by other individuals may be recognized through different mechanisms.
Journal of AnatomyREVIEW: The functional organization of the intraparietal sulcus in humans and monkeys
737 Citations2005Christian Grefkes, Gereon R. Fink
The data suggest that anterior parts of the IPS comprising areas AIP and VIP are relatively well preserved across species, and posterior areas such as area LIP and CIP have been found more medially in humans, possibly reflecting differences in the evolution of the dorsal visual stream and the inferior parietal lobule.
Trends in Cognitive SciencesThe neural bases of complex tool use in humans
702 Citations2003Scott H. Johnson-Frey
These findings indicate that behaviors associated with complex tool use arise from functionally specialized networks involving temporal, parietal and frontal areas within the left cerebral hemisphere.
ScienceMapping of Contralateral Space in Retinotopic Coordinates by a Parietal Cortical Area in Humans
690 Citations2001Martin I. Sereno, Sabrina Pitzalis +1 more
The internal organization of a higher level visual area in the human parietal cortex was mapped and a region in the superior parietal cortex showed robust retinotopic mapping of the remembered target angle.
Journal of NeuroscienceNeural Correlates of Reach Errors
648 Citations2005Jörn Diedrichsen, Yasmin L. Hashambhoy +2 more
The results are inconsistent with the idea that kinematics and dynamics of reaching are computed in separate neural entities and indicate a neural and behavioral dissociation between errors that lead to switching of behavioral goals and errors that Lead to adaptation of internal models of limb dynamics and kinematic.
Experimental Brain ResearchVisually guided grasping produces fMRI activation in dorsal but not ventral stream brain areas
647 Citations2003Jody C. Culham, Stacey L. Danckert +4 more
Functional magnetic resonance imaging results suggest that dorsal areas, including AIP, but not ventral areas such as LOC, play a fundamental role in computing object properties during grasping.
Journal of NeuroscienceFunctional Organization of Human Intraparietal and Frontal Cortex for Attending, Looking, and Pointing
646 Citations2003Serguei V. Astafiev, Gordon L. Shulman +4 more
Surface-based registration of macaque cortical areas onto the map of fMRI responses suggests a relatively good spatial correspondence between human and macaque parietal areas, and large interspecies differences were noted in the topography of frontal areas.
Nature reviews. NeuroscienceThe neuroscience of grasping
613 Citations2005Umberto Castiello
Recent research in behavioural neuroscience, neuroimaging and electrophysiology has the potential to reveal where in the brain the process of grasping is organized, but has yet to address several questions about the sensorimotor transformations that relate to the control of the hands.
Current Opinion in NeurobiologyNeural mechanisms of imitation
609 Citations2005Marco Iacoboni
This work has suggested that there is a core circuitry of imitation comprising the superior temporal sulcus and the 'mirror neuron system', which consists of the posterior inferior frontal gyrus and adjacent ventral premotor cortex, as well as the rostral inferior parietal lobule.
BrainVentral occipital lesions impair object recognition but not object‐directed grasping: an fMRI study
577 Citations2003Thomas W. James, Jody C. Culham +3 more
It is confirmed that D.F.'s visual form agnosia is associated with extensive damage to the ventral stream, and that her spared visuomotor skills are associated with visual processing in the dorsal stream.
Cerebral CortexA Distributed Left Hemisphere Network Active During Planning of Everyday Tool Use Skills
556 Citations2004Scott H. Johnson-Frey, Roger Newman‐Norlund +1 more
Findings from two fMRI studies of healthy, right-handed adults in which an event-related design was used to distinguish regions involved in planning and executing tool use gestures with the dominant right and non-dominant left hands are reported.
NeurologyHuman anterior intraparietal area subserves prehension
555 Citations1998Ferdinand Binkofski, Christian Dohle +5 more
It is shown by optoelectronic movement recordings that patients with cortical lesions involving the anterior lateral bank of the intraparietal sulcus have selective deficits in the coordination of finger movements required for object grasping, whereas reaching is much less disturbed.
Current Opinion in NeurologyEye movement control by the cerebral cortex
552 Citations2004Charles Pierrot‐Deseilligny, Dan Miléa +1 more
Eye movements are increasingly used as a tool to elucidate relatively complex neuropsychological processes such as attention, spatial memory, motivation and decisional processes, and a considerable number of reports dealing with these questions have been observed.
Journal of NeurophysiologyTopographic Maps of Visual Spatial Attention in Human Parietal Cortex
510 Citations2005Michael A. Silver, David Ress +1 more
Visualization of the distribution of temporal phases on a flattened representation of parietal cortex revealed at least two distinct topographically organized cortical areas within the intraparietal sulcus (IPS), each representing the contralateral visual field.
Current Opinion in NeurobiologyMotor functions of the parietal lobe
491 Citations2005Leonardo Fogassi, Giuseppe Luppino
Recent data showed that the inferior parietal lobule codes motor acts in a specific way according to the action in which they are embedded, suggesting that this particular motor organization appears to provide a neural mechanism for higher order cognitive motor functions, including understanding of intention.
Nature NeuroscienceCortical responses to invisible objects in the human dorsal and ventral pathways
481 Citations2005Fang Fang, Sheng He
Using fMRI, it is shown that even though observers are completely unaware of test object images owing to interocular suppression, their dorsal cortical areas demonstrate substantial activity for different types of visual objects, with stronger responses to images of tools than of human faces.
Journal of NeuroscienceGoal Representation in Human Anterior Intraparietal Sulcus
468 Citations2006Antonia F. de C. Hamilton, Scott T. Grafton
It is demonstrated that the anterior intraparietal sulcus represents the goal of an observed action in an event-related functional magnetic resonance imaging experiment.
Trends in Cognitive SciencesThe topography of high-order human object areas
465 Citations2002Rafael Malach, Ifat Levy +1 more
It is proposed that resolution needs are an important factor in organizing object representations: objects whose recognition depends on analysis of fine detail will be associated with central-biased representations, whereas objects whose Recognition entails large-scale integration will be more peripherally biased.
NeuropsychologiaThe role of parietal cortex in visuomotor control: What have we learned from neuroimaging?
460 Citations2005Jody C. Culham, Cristiana Cavina‐Pratesi +1 more
The areas discovered by human neuroimaging are reviewed, including the putative functional equivalents of the following macaque regions: parietal eye fields (PEF), ventral intraparietal (VIP) area, parietal reach region (PRR) and the anterior intra parietal (AIP) areas.
NatureShape selectivity in primate lateral intraparietal cortex
445 Citations1998Anne B. Sereno, John H. R. Maunsell
It is shown that many neurons in primate posterior parietal cortex show sensory shape selectivities to simple, two-dimensional geometric shapes while the animal performs a simple fixation task, and these units show shape selectivity equivalent to any shown in the ventral pathway.
Trends in NeurosciencesThe TINS Lecture The parietal association cortex in depth perception and visual control of hand action
425 Citations1997H Sakata, M. Taira +3 more
The dorsal visual pathway is divided into at least two subsystems, V5A, PP and VIP areas for motion vision and V6, LIP and cIPS areas for coding position and 3-D features.
Experimental Brain ResearchFMRI evidence for a 'parietal reach region' in the human brain
407 Citations2003Jason D. Connolly, Richard A. Andersen +1 more
Event-related functional magnetic resonance imaging was used to examine activation in the posterior parietal cortex when subjects made pointing movements or saccades to the same spatial location and concluded that activation in this region is related to specific motor intent.
Journal of NeuroscienceGaze-Centered Updating of Visual Space in Human Parietal Cortex
406 Citations2003W. Pieter Medendorp, Herbert C. Goltz +2 more
Using event-related functional magnetic resonance imaging, an analogous bilateral region in the human PPC is identified that shows contralateral topography for memory-guided eye movements and arm movements that shows dynamically updates the spatial goals for action in a gaze-centered frame.
Nature NeuroscienceVirtual lesions of the anterior intraparietal area disrupt goal-dependent on-line adjustments of grasp
390 Citations2005Eugene Tunik, Scott H. Frey +1 more
It is argued that aIPS is critical for dynamic error detection during goal-dependent reach-to-grasp action that is visually guided and attributes a rapid control process on the basis of visual feedback to aIPS.
ScienceObserving Others: Multiple Action Representation in the Frontal Lobe
351 Citations2005Koen Nelissen, Giuseppe Luppino +3 more
Investigation of whether other monkey frontal areas respond to actions performed by others activates monkey ventral premotor cortex, where action meaning, but not object identity, is coded.
Cerebral CortexCortical Control of Visually Guided Reaching: Evidence from Patients with Optic Ataxia
350 Citations2005Hans‐Otto Karnath, Marie-Thérèse Perenin
There is no evidence for the assumption that disruption of visually guided reaching in humans is associated with a lesion typically centering on the SPL on the convexity, and new tools for lesion analysis find this view re-evaluated.
NeuropsychologiaTool use and mechanical problem solving in apraxia
343 Citations1998Georg Goldenberg, Sonja Hagmann
The finding that mechanical problem solving is invariably defective in apraxic patients who commit errors with familiar tools is in good accord with clinical observations, as the gravity of their errors goes beyond what one would expect as a mere sequel of loss of access to instruction of use.
Cognitive Brain ResearchOn beyond mirror neurons: Internal representations subserving imitation and recognition of skilled object-related actions in humans
337 Citations2005Laurel J. Buxbaum, Kathleen M. Kyle +1 more
Journal of Cognitive NeuroscienceReference Frames for Spatial Cognition: Different Brain Areas are Involved in Viewer-, Object-, and Landmark-Centered Judgments About Object Location
334 Citations2004Giorgia Committeri, Gaspare Galati +4 more
Results strongly demonstrate that viewer-centered (egocentric) coding is restricted to the dorsal stream and connected frontal regions, whereas a coding centered on external references requires both dorsal and ventral regions, depending on the reference being a movable object or a landmark.
Journal of NeuroscienceDistinct Cortical Pathways for Processing Tool versus Animal Sounds
331 Citations2005James W. Lewis, Julie A. Brefczynski +3 more
The data suggest that the recognition processing for some sounds involves a causal reasoning mechanism (a high-level auditory “how” pathway), automatically evoked when attending to hand-manipulated tool sounds, that effectively associates the dynamic motor actions likely to have produced the sound(s).
NeuronTwo Cortical Systems for Reaching in Central and Peripheral Vision
331 Citations2005Jérôme Prado, Simon Clavagnier +4 more
Results show that reaching to the peripheral visual field engages a more extensive cortical network thanreaching to the central visual field, differently modulated by the two conditions.
Cognitive Brain ResearchCortical topography of human anterior intraparietal cortex active during visually guided grasping
328 Citations2005Scott H. Frey, Deborah Vinton +2 more
Activation in the human anterior intraparietal sulcus during visually guided grasping suggests a homologue of macaque area AIP, which is likely within the most superior, rostral aspect of Brodmann's area 40, corresponding to area PF or PDE asdefined by von Economo and Koskinas, and area 86 as defined by Vogt and colleagues.
Experimental Brain ResearchRole of the medial parieto-occipital cortex in the control of reaching and grasping movements
324 Citations2003Claudio Galletti, Dieter F. Kutz +3 more
The picture emerging from data is that the medial parieto-occipital cortex is well equipped to control both proximal and distal movements in the online visuomotor guidance of prehension, and selective V6A lesions in monkey produce misreaching and misgrasping with the arm contralateral to the lesion in visually guided movements, suggesting that human and monkey superior parietal lobules are homologous structures.
NeuronCrossmodal Processing of Object Features in Human Anterior Intraparietal Cortex
310 Citations2002Christian Grefkes, Peter H. Weiss +2 more
It is suggested that this area in anterior IPS is the human equivalent of macaque area AIP, and neural activity in this area was further enhanced when subjects transferred object information between modalities (crossmodal matching).
NeuronSpatial Updating in Human Parietal Cortex
303 Citations2003Elisha P. Merriam, Christopher R. Genovese +1 more
This work scans subjects during a task that involved remapping of visual signals across hemifields and demonstrates that updating of visual information occurs in human parietal cortex.
Cognitive Brain ResearchNeural representations of graspable objects: are tools special?
297 Citations2004Sarah H. Creem-Regehr, James N. Lee
It is suggested that the functional identity of graspable objects influences the extent of motor representations associated with them, and these results have implications for understanding the interactions between "what" and "how" visual processing systems.
Journal of NeuroscienceThe Processing of Visual Shape in the Cerebral Cortex of Human and Nonhuman Primates: A Functional Magnetic Resonance Imaging Study
273 Citations2004Katrien Denys, Wim Vanduffel +5 more
The shape-sensitive regions in occipital, temporal, and parietal cortex of both humans and macaques can be used to constrain the warping of monkey to human cortex and suggest a large expansion of lateral parietal and superior temporal cortex in humans compared with monkeys.
NeuronFunctional Magnetic Resonance Imaging of Macaque Monkeys Performing Visually Guided Saccade Tasks
273 Citations2004Minoru Koyama, Isao Hasegawa +4 more
NeuroImageHuman medial intraparietal cortex subserves visuomotor coordinate transformation
267 Citations2004Christian Grefkes, Afra Ritzl +2 more
The data suggest that the human medial intraparietal cortex subserves visuomotor transformation processes to control goal-directed hand movements independently from the modality-specific processing of visual or proprioceptive information.
Journal of NeurophysiologyTopographic Organization for Delayed Saccades in Human Posterior Parietal Cortex
265 Citations2005Denis Schluppeck, Paul W. Glimcher +1 more
It is shown that human PPC contains at least two topographically organized regions, which are candidates for the human homologue of LIP, and that topographic maps tile the cortex continuously from V1 well into PPC.
NeuronDifferential Effects of Viewpoint on Object-Driven Activation in Dorsal and Ventral Streams
254 Citations2002Thomas W. James, G. Keith Humphrey +3 more
The difference in the pattern of priming-related activation in the two areas may reflect the respective roles of the ventral and dorsal streams in object recognition and object-directed action.
Current Opinion in NeurobiologyThe representation of numerical magnitude
231 Citations2006Elizabeth M. Brannon
An important picture emerging from this research is that adult humans share with non-human animals a system for representing number as language-independent mental magnitudes and that this system emerges early in development.
American PsychologistThe Cinderella of Psychology: The Neglect of Motor Control in the Science of Mental Life and Behavior.
229 Citations2005David Α. Rosenbaum
The neglected study of how decisions are enacted--the focus of motor control research-- has received little attention in psychology and possible reasons are considered.
NeuronDissociation between Ventral and Dorsal fMRI Activation during Object and Action Recognition
228 Citations2005Lior Shmuelof, Ehud Zohary
Dissociation between dorsal and ventral fMRI activation patterns during observation of object manipulation video clips is demonstrated and support the hypothesized functional specialization in the visual system and suggest that parietal areas are engaged in action recognition, as well as in action planning.
NeuropsychologiaDeficient internal models for planning hand–object interactions in apraxia
226 Citations2004Laurel J. Buxbaum, Scott H. Johnson-Frey +1 more
Patients with IM and motor imagery deficits were significantly more likely than the non-apraxic group to have lesions in the intraparietal sulcus, a region previously implicated in imagery for hand-object interactions.
NeuroImageFunctional Brain Mapping of Monkey Tool Use
219 Citations2001Shigeru Obayashi, Tetsuya Suhara +6 more
NeuroImageSpace Coding in Primate Posterior Parietal Cortex
211 Citations2001Frank Bremmer, Anja Schlack +3 more
Functional imaging data on humans reveal a network of cortical areas that respond to polymodal stimuli conveying motion information and it is suggested that this area constitutes the human equivalent of monkey area VIP.
NeuropsychologiaCognitive representations of hand posture in ideomotor apraxia
206 Citations2003Laurel J. Buxbaum, Angela Sirigu +2 more
Accumulation of data suggests degradation of inferior parietally-mediated representations of the precise hand postures associated with familiar objects, consistent with possible over-reliance upon dorsal system procedures for calculating precision and power grip in response to object structure.
Journal of NeurophysiologyIntegration of Target and Effector Information in Human Posterior Parietal Cortex for the Planning of Action
199 Citations2004W. Pieter Medendorp, Herbert C. Goltz +2 more
Not only do these regions code target location, but they also appear to integrate target selection with effector selection, consistent with previous clinical and behavioral studies showing that each hand is more effective in directing movements to targets in ipsilateral visual space.
NeuroImageThe human action recognition system and its relationship to Broca’s area: an fMRI study
189 Citations2003Farsin Hamzei, Michel Rijntjes +4 more
An overlap of activations due to the language production, movement execution, and action recognition was found in the parietal cortex, the left inferior frontal gyrus, and the IFG-PG border (IFG/PG).
NeuropsychologiaExtension of corticocortical afferents into the anterior bank of the intraparietal sulcus by tool-use training in adult monkeys
189 Citations2006Sayaka Hihara, Tomonori Notoya +6 more
These results provide the first concrete evidence for the induction of novel neural connections in the adult monkey cerebral cortex, which accompanies a process of demanding behaviour in these animals.
Journal of NeuroscienceStimulation of the Posterior Parietal Cortex Interferes with Arm Trajectory Adjustments during the Learning of New Dynamics
179 Citations2004Valeria Della‐Maggiore, Nicole Malfait +2 more
A role of PPC in the adjustment of motor commands necessary for adapting to a novel mechanical environment is found to be consistent with that played by posterior parietal cortex in the coordinate transformation necessary for visually guided reaching.
NeuropsychologiaA double dissociation between sensitivity to changes in object identity and object orientation in the ventral and dorsal visual streams: A human fMRI study
178 Citations2005Kenneth F. Valyear, Jody C. Culham +3 more
Differences in BOLD activity in the dorsal and ventral visual streams as a function of object identity and object orientation are consistent with the idea that the dorsal stream plays a critical role in the visual control of object-directed actions while the ventral stream plays an important role in object perception.
CortexA Selective Impairment of Hand Posture for Object Utilization in Apraxia
174 Citations1995Angela Sirigu, Laurent Cohen +4 more
The case of an apraxic patient who was impaired in all aspects of gestural behavior following bilateral posterior parietal cortex lesions is reported, and the existence of specialized cortical mechanisms for the representation and activation of the postural schemata of the hand required for complex actions is proposed.
NeuropsychologiaParietal updating of limb posture: An event-related fMRI study
156 Citations2006Åsa Pellijeff, Leonardo Bonilha +3 more
It is shown that a change in the posture of the upper-limb is associated with a significant increase in BOLD activation in only one brain region--the superior parietal cortex, particularly the medial aspect (precuneus), consistent with the suggestion that this region of the PPC may participate in the dynamic representation of the body schema.
Journal of Neurology Neurosurgery & PsychiatryLocation of the human posterior eye field with functional magnetic resonance imaging.
148 Citations1996René M. Müri, M T Iba-Zizen +3 more
Functional MRI was used during a saccade task to better localise the location of the human parietal eye field, and bilateral activity was seen in the precentral sulcus, corresponding to the frontal eye field and in the deep region of the intraparietal sulcus.
Journal of NeuroscienceEye Position Signal Modulates a Human Parietal Pointing Region during Memory-Guided Movements
139 Citations2000Joseph F. X. DeSouza, Sean P. Dukelow +4 more
The results suggest that the human parietal hand/arm movement region (rIPS), like monkey parietal areas, exhibits an eye position modulation of its activity; modulation that may be used to transform the coordinates of the retinotopically coded target position into a motor error command appropriate for the wrist.
NeuroImageThe role of the dorsal stream for gesture production
138 Citations2005Esteban A. Fridman, Ilka Immisch +7 more
Results demonstrate that not only PPc but also the PMv acts in the processing of sensorimotor information during gestures, which might be the substrate underlying selective deficits in ideomotor apraxia patients.
Cerebral CortexProcessing Shape, Motion and Three-dimensional Shape-from-motion in the Human Cortex
136 Citations2003Scott O. Murray
NeuroImageAutomatized clustering and functional geometry of human parietofrontal networks for language, space, and number
134 Citations2004Olivier Simon, Ferath Kherif +6 more
An automatized clustering algorithm was used to reanalyze published fMRI data and reproduce the previously observed geometrical organization of activations for saccades, attention, grasping, pointing, calculation, and language processing in the parietal lobe, and it is shown that this organization extends to lateral and mesial prefrontal regions.
Journal of NeurophysiologyRemapping the Remembered Target Location for Anti-Saccades in Human Posterior Parietal Cortex
126 Citations2005W. Pieter Medendorp, Herbert C. Goltz +1 more
This fMRI study shows that this region within the human posterior parietal cortex codes the target location for an upcoming saccade, rather than the location of the remembered visual stimulus in an anti-saccade task.
Journal of Cognitive NeuroscienceParietal rTMS Disrupts the Initiation but not the Execution of On-line Adjustments to a Perturbation of Object Size
112 Citations2005Scott Glover, R. Chris Miall +1 more
It was concluded that the left parietal lobe plays a critical role in initiating an on-line adjustment to a change in target size, but not in executing that adjustment.
NeuropsychologiaMotor awareness without perceptual awareness
98 Citations2005Helen Johnson, Patrick Haggard
This work suggests that previous studies of the relation between motor performance and perceptual awareness have confounded two separate dissociations, and proposes a new measure of motor awareness, based on subjects' ability to reproduce the spatial details of reaching movements they have just made.
Current BiologyWhere the Eye Looks, the Hand Follows
87 Citations2005Stephen R. Jackson, Roger Newport +2 more
A patient with a limb-dependent form of optic ataxia who can accurately reach with either hand to objects that he can foveate but who cannot effectively decouple reach direction from gaze direction is reported, indicating an impairment in the ability to dissociate the eye and limb visuomotor systems when appropriate.
Current BiologyWhere the Eye Looks, the Hand FollowsLimb-Dependent Magnetic Misreaching in Optic Ataxia
60 Citations2005Stephen R. Jackson, Roger Newport +2 more
From monkey brain to human brain : a Fyssen Foundation symposium
41 Citations2005Stanislas Dehaene
From Monkey Brain to Human Brain uses the latest findings in cognitive psychology, comparative biology, and neuroscience to look at the complex patterns of convergence and divergence in primate cortical organization and function.
Journal of Motor BehaviorGaze-Dependent Deviation in Pointing Induced by Transcranial Magnetic Stimulation Over the Human Posterior Parietal Cortex
20 Citations2005Paul van Donkelaar, Jaymi Adams
It is demonstrated that during visual fixation, eye-position signals can dominate pointing responses when the activity in the PPC contralateral to the moving limb is disrupted with transcranial magnetic stimulation (TMS).
…