Time course of improvement in left ventricular function, mass and geometry in patients with congestive heart failure treated with beta-adrenergic blockade
Journal of the American College of CardiologyPublished 1 April 1995
Shelley Hall, Carlos G. Cigarroa, Lucille Marcoux, Richard C. Risser, Paul Grayburn, Eric J. Eichhorn
Citations535
SJR quartileQ1
SJR score9.02
SNIP6.30
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TL;DR
Long-term therapy with metoprolol results in a reversal of maladaptive remodeling with reduction in left ventricular volumes, regression ofleft ventricular mass and improved ventricular geometry by 18 months.
Abstract
Patients with heart failure treated with metoprolol do not demonstrate an improvement in systolic performance until after 1 month of therapy and may have a mild reduction in function initially. Long-term therapy with metoprolol results in a reversal of maladaptive remodeling with reduction in left ventricular volumes, regression of left ventricular mass and improved ventricular geometry by 18 months.
Keywords
Medicine
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