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Neurocognitive dimensions characterising patients with first-episode psychosis

The British Journal of PsychiatryPublished 1 September 2002Open access
Svein Friis, Kjetil Sundet, B.R. Rund, Per Vaglum, Thomas H. McGlashan
Citations67
SJR quartileQ1
SJR score2.47
SNIP2.17
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TL;DR

Neurocognitive function in first-episode psychosis is described by at least five independent dimensions, with significant findings that the MS score was higher for men, and the WM and VL scores were correlated with years of education.

Abstract

BACKGROUND: Assessment of neurocognitive dysfunction in schizophrenia is hampered by the multitude of tests used in the literature. AIMS: We aimed to identify the main dimensions of an assessment battery for patients with first-episode psychosis and to estimate the relationship between dimension scores and gender, age, education, diagnosis and symptoms. METHOD: Eight frequently used neuropsychological tests were used. We tested 219 patients 3 months after start of therapy or at remission, whichever occurred first. RESULTS: We identified five dimensions: working memory (WM); verbal learning (VL); executive function (EF); impulsivity (im); and motor speed (MS). Significant findings were that the MS score was higher for men, and the WM and VL scores were correlated with years of education. CONCLUSIONS: Neurocognitive function in first-episode psychosis is described by at least five independent dimensions.

Keywords

PsychologyMedicineArts and Humanities