Serotonin Receptor Subtypes: Pharmacological Significance and Clinical Implications

The 5-HT receptors modulate glutamate release in cerebellum and cholecystokinin release in nucleus accumbens and possible relevance to cerebellar ataxias and to anxiety, M. Raiteri et al serotonin and eating disorders - pharmacological relationships.

Abstract

Molecular analysis of serotonin receptor subtypes, R.L. Weinshank 5-HT1 receptor subtypes - pharmacological heterogeneity, M.C. Miguel and M. Hamon 5HT2-receptors - location, pharmacological, pathological and physiological role, J.E. Leysen pharmacological relevance of 5-HT3 receptors, J.R. Fozard uptake mechanisms and drug development, R.W. Fuller animal models of anxiety and aggression in the study of serotonergic agents, B. Olivier et al electrophysiological evidence for the distinct properties of presynaptic and postsynaptic 5-HT1A receptors - possible clinical relevance, C. de Montigny and P. Blier current concepts of the role of serotonin function in depression and anxiety, D.S. Charney and P.L. Delgado different 5-HT receptors modulate glutamate release in cerebellum (5-HT1 and 5-HT2) and cholecystokinin release in nucleus accumbens (5-HT3) - possible relevance to cerebellar ataxias and to anxiety, M. Raiteri et al serotonin and eating disorders - pharmacological relationships, G. Curzon 5-hydroxytryptamine receptors and drug discovery, P.P.A. Humphrey.