New Users of Antipsychotic Medications Among Children Enrolled in TennCare
Archives of Pediatrics and Adolescent MedicinePublished 1 August 2004
William O. Cooper, Gerald B. Hickson, Cathérine Fuchs, Patrick G. Arbogast, Wayne A. Ray
Citations171
Generate an AI Snapshot to get a quick, structured summary of this paper.
Study Snapshot
ObjectiveStudy objective
MethodsResearch methodology
PopulationPopulation studied
Sample sizeSample sizes
OutcomesStudy outcomes here
ResultsStudy results comes here
LimitationsResearch study limitations comes here
A concise AI-generated summary of the paper will appear here once you click Generate AI Snapshot.
TL;DR
The proportion of TennCare children who became new users of antipsychotics nearly doubled from 1996 to 2001, with a substantial increase in use of antippsychotics for attention-deficit/hyperactivity disorder, conduct disorder, and affective disorders.
Abstract
The proportion of TennCare children who became new users of antipsychotics nearly doubled from 1996 to 2001, with a substantial increase in use of antipsychotics for attention-deficit/hyperactivity disorder, conduct disorder, and affective disorders.
Keywords
PsychologyMedicine
New England Journal of MedicineRisperidone in Children with Autism and Serious Behavioral Problems
1,567 Citations2002James T. McCracken, James J. McGough +27 more
Risperidone was effective and well tolerated for the treatment of tantrums, aggression, or self-injurious behavior in children with autistic disorder and the benefit was maintained at six months.
JAMATrends in the Prescribing of Psychotropic Medications to Preschoolers
867 Citations2000Julie M. Zito
Sizable increases in prevalence were noted between 1991 and 1995 across the 3 sites for clonidine, stimulants, and antidepressants, while neuroleptic use increased only slightly.
Archives of Pediatrics and Adolescent MedicinePsychotropic Practice Patterns for Youth
525 Citations2003Julie M. Zito, Daniel J. Safer +7 more
Youth psychotropic treatment utilization during the 1990s nearly reached adult utilization rates, and youth findings can be used to accurately assess the duration of treatment and unforeseen practice pattern changes, and to identify safety concerns.
American Journal of PsychiatryA Novel Augmentation Strategy for Treating Resistant Major Depression
509 Citations2001Richard C. Shelton, Gary D. Tollefson +10 more
Olanzapine plus fluoxetine demonstrated superior efficacy for treating resistant depression compared to either agent alone.
Archives of General PsychiatryA Double-blind, Placebo-Controlled Study of Risperidone in Adults With Autistic Disorder and Other Pervasive Developmental Disorders
415 Citations1998Christopher J. McDougle, Janice P. Holmes +4 more
Risperidone is more effective than placebo in the short-term treatment of symptoms of autism in adults and well tolerated, with no evidence of extrapyramidal effects, cardiac events, or seizures.
American Journal of PsychiatryZiprasidone in the Treatment of Acute Bipolar Mania: A Three-Week, Placebo-Controlled, Double-Blind, Randomized Trial
372 Citations2003Paul E. Keck, Márcio Versiani +5 more
Ziprasidone monotherapy was significantly superior to placebo in reducing symptoms of acute mania in patients with bipolar I disorder.
American Journal of EpidemiologyRecall Accuracy for Prescription Medications: Self-report Compared with Database Information
349 Citations1995Suzanne L. West, David A. Savitz +4 more
This study suggests significant underascertainment of self-reported prescription drug exposure but little evidence that exposures are overreported.
Journal of the American Academy of Child & Adolescent PsychiatryEffects of Risperidone on Conduct and Disruptive Behavior Disorders in Children With Subaverage IQs
336 Citations2002R. E. Snyder, Atilla Turgay +4 more
Risperidone appears to be an adequately tolerated and effective treatment in children with subaverage IQs and severe disruptive behaviors such as aggression and destructive behavior.
American Journal of EpidemiologyUSE OF MEDICAID DATA FOR PHARMACOEPIDEMIOLOGY
316 Citations1989Wayne A. Ray, Marie R. Griffin
This paper reviews methodological problems and describes pragmatic solutions that have been developed through the ongoing use of these data bases for epidemiologic studies.
BiometricsAnalysis of Covariance and Standardization as Instances of Prediction
312 Citations1982P. W. Lane, J. A. Nelder
Prediction provides the basis for unifying the procedures of covariances adjustment and standardization in epidemiology and demography.
Journal of the American Academy of Child & Adolescent PsychiatryWeight Gain Associated With Olanzapine and Risperidone in Adolescent Patients: A Comparative Prospective Study
238 Citations2002G Ratzoni, Doron Gothelf +7 more
Olanzapine and risperidone are associated with extreme weight gain in adolescents, much higher than that reported in adults, especially in patients at high risk.
Journal of the American Academy of Child & Adolescent PsychiatryOlanzapine Versus Haloperidol in Children With Autistic Disorder: An Open Pilot Study
188 Citations2001Richard P. Malone, Jacqueline Cater +3 more
The findings suggest that olanzapine is a promising treatment for children with autistic disorder and further placebo-controlled and long-term studies of olanZapine in autistic disorder are required.
Journal of Clinical EpidemiologyA retrospective cohort study of diabetes mellitus and antipsychotic treatment in the United States
177 Citations2003John B. Buse
An increased risk of developing diabetes compared with the AdvancePCS general patient population was observed during treatment with conventional or atypical antipsychotics.
Health AffairsMedicaid And Mental Health: Be Careful What You Ask For
174 Citations2003Richard G. Frank, Howard H. Goldman +1 more
Medicaid mental health policy has expanded access, fostered consumerism, and created incentives for expansion of community-based providers, and has dramatically changed the economic rules governing public mental health care.
The British Journal of PsychiatryAntipsychotic-induced hyperprolactinaemia in women: pathophysiology, severity and consequences
167 Citations2003Angelika Wieck, Peter Haddad
Antipsychotic-induced hyperprolactinaemia should become a focus of interest in the drug treatment of psychiatric patients and its consequences require further research but are likely to include premature bone loss.
American Journal of PsychiatryConcomitant Psychotropic Medication for Youths
166 Citations2003Daniel J. Safer, Julie M. Zito +1 more
Substantive systematic evidence is needed to clarify this increasingly common, inadequately researched child psychopharmacologic practice.
Journal of the American Geriatrics SocietyComparing Sources of Drug Data about the Elderly
143 Citations1991Richard E. Johnson, William M. Vollmer
This project assessed the extent of agreement between drug‐taking data obtained from an in‐home assessment and that obtained from a automated outpatient pharmacy system and from a mail questionnaire.
Journal of Child and Adolescent PsychopharmacologyRisperidone in the Treatment of Behavioral Disturbances in Children and Adolescents with Borderline Intellectual Functioning: A Double-Blind, Placebo-Controlled Pilot Trial
138 Citations2001Marc van Bellinghen, C Troch
Short-term risperidone treatment was well tolerated and significantly more effective than placebo in controlling behavioral disturbances in children with low IQ.
Epidemiologic ReviewsUSE OF AUTOMATED DATABASES FOR PHARMACOEPIDEMIOLOGY RESEARCH
136 Citations1990Brian L. Strom, Jeffrey L. Carson
Journal of the American Academy of Child & Adolescent PsychiatryAntipsychotics in Children and Adolescents
117 Citations1999Magda Campbell, Judith L. Rapoport +1 more
A critical overview of the available evidence for the efficacy and safety of antipsychotic agents in children and adolescents is presented and knowledge gaps and needs for further research are identified.
Journal of the American Academy of Child & Adolescent PsychiatrySummary of the Practice Parameters for the Assessment and Treatment of Children, Adolescents, and Adults With ADHD
106 Citations1997Mina K. Dulcan, Rod Benson
This summary of the practice parameters describes the assessment, differential diagnosis, and treatment of children, adolescents, and adults who present with symptoms of attention-deficit/hyperactivity disorder.
Journal of the American Academy of Child & Adolescent PsychiatryOpen Trial of Risperidone in 24 Young Children With Pervasive Developmental Disorders
104 Citations2001Gabriele Masi, Angela Cosenza +2 more
Low-dose risperidone may positively affect symptoms in young autistic children, improving disruptive/hyperactive behavior and affective dysregulation and further controlled studies in this age group are warranted.
JAMATennessee's Failed Managed Care Program for Mental Health and Substance Abuse Services
96 Citations1998Cyril F. Chang
It is pointed out that the TennCare Partners program's difficulties stemmed directly from a flawed design that spread funds previously earmarked for severely mentally ill patients across the entire Medicaid population.
PEDIATRICSPsychopharmacology for Young Children: Clinical Needs and Research Opportunities
85 Citations2001Benedetto Vitiello
Possible approaches to expanding the research basis of this area of clinical practice, including a recently started study of methylphenidate in preschoolers, are reported here.
Clinical TherapeuticsZiprasidone: An atypical antipsychotic drug for the treatment of schizophrenia
82 Citations2002Glen L. Stimmel, Mary A. Gutierrez +1 more
Ziprasidone differs from other atypical antipsychotic drugs in several clinically important ways, although further experience is necessary to clarify the significance of these differences.
Journal of Child and Adolescent PsychopharmacologyPrevalence and Patterns of Psychotropic and Anticonvulsant Medication Use in Children and Adolescents Referred to Residential Treatment
68 Citations1998Daniel F. Connor, KAAN R. OZBAYRAK +2 more
The high prevalence of psychiatric and antiepileptic medication use in children and adolescents admitted to a residential treatment facility, and especially the pattern of their use, raises questions about prescribing practices for youths entering residential treatment and about pediatric psychopharmacotherapy in general.
PubMedTreatment of aggression in children and adolescents with autism and conduct disorder.
67 Citations2003Christopher J. McDougle, Kimberly A. Stigler +1 more
Medication treatments for youngsters with autistic disorder and conduct disorder, conditions for which the pharmacologic management of aggression is often necessary, are reviewed.
Clinical TherapeuticsDifferential effects of antipsychotic agents on the risk of development of type 2 diabetes mellitus in patients with mood disorders
62 Citations2003Frank D. Gianfrancesco, Amy Grogg +3 more
It is suggested that some antipsychotics may increase the risk for the development of type 2 diabetes in patients with mood disorders and that the effect may vary by drug.
Medical CareA Comparison of Patient Drug Regimens as Viewed by the Physician, Pharmacist and Patient
45 Citations1981Katherine A. Leister, W. A. EDWARDS +2 more
The highest degree of congruence occurred between hospital discharge medication notes and outpatient drug profile records, indicating a substantial degree of inconsistent as well as incomplete drug records within the same setting.
Archives of Pediatrics and Adolescent MedicineChanges in Continuity of Enrollment Among High-Risk Children Following Implementation of TennCare
21 Citations1999William O. Cooper, Gerald B. Hickson +2 more
For infants in the first year of life and for children hospitalized with a chronic health condition, implementation of TennCare improved continuity of coverage.
Journal of the American Academy of Child & Adolescent PsychiatryZIPRASIDONE-ASSOCIATED GALACTORRHEA IN A FEMALE TEENAGER
21 Citations2003Mirlande P. Jordan
The Canadian Journal of PsychiatryAssessment and Management of Antipsychotic-Induced Adverse Events
20 Citations1998Leonardo Cortese, Emmanuelle Pourcher-Bouchard +1 more
The availability of the newer atypical antipsychotics offers another alternative, because they are associated with a much lower incidence of antipsychotic-induced side effects, and can help encourage patient compliance and improve the outcome of antip psychosis treatment.