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Home / Papers / Chlorinated Solvents: Their Advantages, Disadvantages, and Alternatives in Organic and...

Chlorinated Solvents: Their Advantages, Disadvantages, and Alternatives in Organic and Medicinal Chemistry

DOI: 10.1021/acs.chemrev.0c00709Source
144 Citations•2020•
Andrew Jordan, Patrick Stoy, Helen F. Sneddon
Chemical Reviews

This review explores the properties that led to such widespread use of chlorinated solvents, why there is now an increasing drive to minimize usage, and what alternatives are currently available.

Abstract

Chlorinated solvents were once, and in many places are still, ubiquitous in chemistry laboratories. This review explores the properties that led to such widespread use, why there is now an increasing drive to minimize usage, and what alternatives are currently available.