Enrichment of Low‐Abundance Peptides and Proteins on Zeolite Nanocrystals for Direct MALDI‐TOF MS Analysis
Angewandte Chemie International EditionPublished 15 December 2004Open access
Yahong Zhang, Xiaoyan Wang, Wei Shan, Biyun Wu, Huizhi Fan, Xijuan Yu
Citations105
SJR quartileQ1
SJR score5.55
SNIP2.47
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Abstract
Concentrated efforts: A zeolite-nanocrystal-mediated enrichment procedure that doubles as a desalting step allows low-abundance proteins to be readily detected with MALDI-TOF MS (see picture). Mass spectral signal-to-noise ratios are greatly improved for a wide range of peptides, which underscores the potential of this procedure to boost proteomics research.
Keywords
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