Risk factors for amphotericin B-associated nephrotoxicity
The American Journal of MedicinePublished 1 November 1989
Melanie Fisher, George H. Talbot, Greg Maislin, Bernadette P. McKeon, Kevin P. Tynan, Brian L. Strom
Citations127
SJR quartileQ1
SJR score1.00
SNIP1.04
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TL;DR
Risk factors for amphotericin B-associated nephrotoxicity include higher average daily doses, diuretic use, and abnormal baseline renal function, which suggest possible protective interventions and will aid clinicians in assessing the risk-benefit ratio of amphoteric in B therapy for deep fungal infection.
Abstract
Risk factors for amphotericin B-associated nephrotoxicity include higher average daily doses (approximately a doubling for each 0.10 mg/kg/day increment), diuretic use, and abnormal baseline renal function. These data suggest possible protective interventions and will aid clinicians in assessing the risk-benefit ratio of amphotericin B therapy for deep fungal infection.
Keywords
MedicinePharmacology, Toxicology and Pharmaceutics
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