Amino Acids in Plasma and CSF and Monoamine Metabolites in CSF: Interrelationship in Healthy Subjects
Journal of NeurochemistryPublished 1 March 1984
Lars Hagenfeldt, L. Bjerkenstedt, Gunnar Edman, Göran Sedvall, F.‐A. Wiesel
Citations73
SJR quartileQ1
SJR score1.50
SNIP1.02
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TL;DR
Sex differences were observed in both plasma and CSF amino acid levels as well as in the relationship between these concentrations, and the MOPEG level in CSF correlated positively with the plasma concentrations of several amino acids.
Abstract
Plasma and cerebrospinal fluid (CSF) concentrations of amino acids were measured in 65 healthy volunteers (50 men and 15 women). The CSF levels of the monoamine metabolites homovanillic acid (HVA), 3-methoxy-4-hydroxyphenylethylene glycol (MOPEG), and 5-hydroxyindoleacetic acid (5-HIAA) were also determined. Sex differences were observed in both plasma and CSF amino acid levels as well as in the relationship between these concentrations. No significant correlations were observed between the CSF levels of HVA and 5-HIAA, and the concentrations of their precursor amino acids in either plasma or CSF. The MOPEG level in CSF correlated positively with the plasma concentrations of several amino acids.
Keywords
MedicineBiochemistry, Genetics and Molecular Biology
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