RISK FACTORS FOR KAPOSI'S SARCOMA IN HOMOSEXUAL MEN
The LancetPublished 1 May 1982
Michael Marmor, L Laubenstein, DanielC. William, Alvin E. Friedman‐Kien, Russ Byrum, Sam E. D'Onofrio
Citations243
SJR quartileQ1
SJR score12.11
SNIP22.72
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TL;DR
Multivariate analysis indicated independent significant associations for amyl nitrite and sexual activity and showed use of phencyclidine, methaqualone, and ethyl chloride to be non-significant.
Abstract
An investigation of 20 homosexual men with histologically confirmed Kaposi's sarcoma and 40 controls revealed significant associations between Kaposi's sarcoma and use of a number of drugs (amyl nitrite, ethyl chloride, cocaine, phencyclidine, methaqualone, and amphetamine), history of mononucleosis, and sexual activity in the year before onset of the disease. Patients with Kaposi's sarcoma also reported substantially higher rates of sexually transmitted infections than did controls. Multivariate analysis indicated independent significant associations for amyl nitrite and sexual activity and showed use of phencyclidine, methaqualone, and ethyl chloride to be non-significant. Evaluated at the median exposure for patients, the analysis yielded risk-ratio estimates of 12.3 for amyl nitrite (95% confidence limits 4.2, 35.8) and 2.0 for sexual activity (95% confidence limits 1.3, 3.1).
Keywords
Medicine
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