Use of laboratory tests and clinical symptoms for identification of primary HIV infection
AIDSPublished 1 May 2002
Frederick Hecht, Michael P. Busch, B. D. Rawal, Marcy Webb, Eric Rosenberg, Melinda Swanson
Citations294
SJR quartileQ1
SJR score1.21
SNIP0.90
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TL;DR
Rash and fever indicated the highest risk of primary HIV infection (PHI), and HIV-1 RNA tests are very sensitive for PHI but false-positive results occur.
Abstract
Rash and fever indicated the highest risk of PHI. HIV-1 RNA tests are very sensitive for PHI but false-positive results occur. False-positive results can be reduced through duplicate testing and considering tests < 5000 copies/ml as indeterminate results requiring additional testing. p24 antigen was more specific than HIV-1 RNA testing but less sensitive.
Keywords
Immunology and MicrobiologyMedicine
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