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Serum testosterone levels decrease in middle age in women with the polycystic ovary syndrome

Fertility and SterilityPublished 1 April 2000
Stephen J. Winters, Evelyn O. Talbott, David S. Guzick, Jeanne V. Zborowski, Kathleen P. McHugh
Citations177
SJR quartileQ1
SJR score2.03
SNIP2.05

TL;DR

Testosterone levels were increased in younger and older women with PCOS compared with controls but were similar to controls in women 42–47 years of age, and may contribute to their increased risk for cardiovascular disease, endometrial cancer, and other diseases.

Abstract

Hyperandrogenism partly resolves before menopause in women with PCOS. This change may explain the tendency of women with PCOS to cycle regularly as they grow older. Testosterone levels remain elevated in older women with PCOS, however, and may contribute to their increased risk for cardiovascular disease, endometrial cancer, and other diseases.

Keywords

Medicine