Etiology of Extubation Failure and the Predictive Value of the Rapid Shallow Breathing Index
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TL;DR
This study confirms the high PPV for an f/VT < 100 and defines the etiology of the 20% false-positive rate (FPR), which is best explained by extubation failure caused by processes for which f/ VT is physiologically or temporally unlikely to predict success or failure.
Abstract
Failure of weaning from mechanical ventilation is thought to result from an imbalance between respiratory muscle capacity and respiratory demand. The ratio of respiratory rate to tidal volume (f/VT, rapid shallow breathing index) during spontaneous unsupported respiration increases when this imbalance exists, and may predict the success or failure of weaning from mechanical ventilation. Using f/VT, Yang and Tobin demonstrated a positive predictive value (PPV) of 0.78 (f/VT or = 100, four required reintubation, all because of the underlying respiratory process. This study confirms the high PPV for an f/VT or = 100 but extubation success) for f/VT may be lower than previously reported.
