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Cocaine seeking over extended withdrawal periods in rats: different time courses of responding induced by cocaine cues versus cocaine priming over the first 6 months

PsychopharmacologyPublished 7 April 2004
Lin Lü, Jeffrey W. Grimm, Jack Dempsey, Yavin Shaham
Citations170
SJR quartileQ1
SJR score1.16
SNIP0.97

TL;DR

Results indicate that the withdrawal period is a critical modulator of drug seeking provoked by re-exposure to cocaine cues, but not cocaine itself, and that while the incubation of responsiveness to cocaine cue is a long lasting phenomenon, it is not permanent.

Abstract

Results indicate that the withdrawal period is a critical modulator of drug seeking provoked by re-exposure to cocaine cues, but not cocaine itself. Results also indicate that while the incubation of responsiveness to cocaine cues is a long lasting phenomenon, it is not permanent.

Keywords

Neuroscience