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Automated Proton Spectroscopic Image Processing

Journal of Magnetic Resonance Series BPublished 1 January 1995
Timothy J. Doyle, Ravi Pathak, Jerry S. Wolinsky, Ponnada A. Narayana
Citations20

TL;DR

An automatic data processing and display protocol for proton magnetic resonance spectroscopic imaging is described, which is robust, simple to use, and minimizes user bias in processing and quantifying serial changes of metabolite levels in brain tissue.

Abstract

An automatic data processing and display protocol for proton magnetic resonance spectroscopic imaging is described. The spectroscopic images are generated using the fitted peak areas of phased metabolite resonances using the Levenberg-Marquardt algorithm. This automated spectroscopic image processing is tested and evaluated using phantom and human brain data. This algorithm is robust, simple to use, and minimizes user bias in processing and quantifying serial changes of metabolite levels in brain tissue.

Keywords

MedicineBiochemistry, Genetics and Molecular Biology