A case of centric fission in man
HumangenetikPublished 1 September 1975
Susanne Hansen
Citations34
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TL;DR
Centric fission of chromosome 7 was found in an otherwise normal karyotype resulting in two stable telocentrics with no tendency to fuse again.
Abstract
Centric fission of chromosome 7 was found in an otherwise normal karyotype resulting in two stable telocentrics with no tendency to fuse again.
Keywords
Agricultural and Biological SciencesBiochemistry, Genetics and Molecular Biology
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A convenient measuring technique has been developed for the rapid and accurate recording of fluorescence patterns in human metaphase chromosomes that should be particularly valuable for the identification of chromosomes 4–5 and the individual types in the 6–12 group.
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Through modifications of the original methods used in the DNA hybridization work, techniques have been developed which make each chromosome identifiable and these observations were later made on human chromosomes.
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A major role had been played by centric fission as well as fusion, translocation, and pericentric inversion in birds to elucidate mechanisms involved in certain structural changes of macrochromosomes observed in birds.
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41 Citations1969D. I. Southern
It is proposed that, contrary to certain beliefs, centric fission may have played an important role during karyotype evolution in the Acrididae.
HereditasChromosome polymorphism in the root vole (Microtus oeconomus)
38 Citations2009Karl Fredga, Ulf Bergström
In an isolated population of root voles chromosomal polymorphism of the Robertsonian type was discovered and was caused by centric fission of one chromosome pair (m8).
Human HeredityA Human Family Suggesting Evidence for Centric Fission and Stability of a Telocentric Chromosome
37 Citations1972Anil K. Sinha, Sen Pathak +1 more
It is interpreted that during the embryonic life of the female carrier, one of the cells with the translocation D/D-chromosome underwent centric misdivision that was followed by a pericentric inversion in one ofThe female carrier's telocentrics apparently gave to a stable telocentric D- chromosome and a regular D-group chromosome.
Cellular and Molecular Life SciencesA possible case of centric fission in a primate
20 Citations1971J. Egozcue
Estudios cromosómicos llevados a cabo en un macho dePresbytis entellus sugieren que los mecanicos de fisión céntrica han intervenido en the evolución cromsómica oficial de los mamíferos, y que thefisión puede producir cromOSomas telocéntricos estables.