Relationship Between a GABA<sub>A</sub>α6 Pro385Ser Substitution and Benzodiazepine Sensitivity
American Journal of PsychiatryPublished 1 September 1999
Nakao Iwata, Deborah S. Cowley, Marta Radel, Peter Roy‐Byrne, David Goldman
Citations85
SJR quartileQ1
SJR score5.27
SNIP3.68
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TL;DR
The authors detected a Pro385Ser [1236C>T] amino acid substitution in the human GABAAa6 that may influence alcohol sensitivity and found it associated with less diazepam-induced impairment of saccadic velocity but not with smooth pursuit gain.
Abstract
The Pro385Ser genotype may play a role in benzodiazepine sensitivity and conditions, such as alcoholism, that may be correlated with this trait.
Keywords
NeuroscienceNursing
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