A Gene Expression Signature Predicts Survival of Patients with Stage I Non-Small Cell Lung Cancer
PLoS MedicinePublished 20 December 2006Open access
Yan Lü, William J. Lemon, Peng-yuan Liu, Yijun Yi, Quaid Morris, Ping Yang
Citations321
SJR quartileQ1
SJR score4.28
SNIP3.21
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TL;DR
A gene expression signature consisting of 64 genes that is highly predictive of which stage I lung cancer patients may benefit from more aggressive therapy is identified, useful in predicting survival of stage I NSCLC and might be useful in informing treatment decisions.
Abstract
Our results indicate that gene expression signatures from several datasets can be reconciled. The resulting signature is useful in predicting survival of stage I NSCLC and might be useful in informing treatment decisions.
Keywords
MedicineBiochemistry, Genetics and Molecular Biology
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