A heuristic method to reconstruct the history of sequences subject to recombination
Journal of Molecular EvolutionPublished 1 April 1993
Jotun Hein
Citations241
SJR quartileQ1
SJR score0.82
SNIP0.55
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TL;DR
This study investigates ways to describe their evolutionary history and proposes a method giving a partial reconstruction of this history, implemented in a program, RecPars, and was used to analyze nine retroviruses.
Abstract
Sequences subject to recombination and gene conversion defy phylogenetic analysis by traditional methods since their evolutionary history cannot be adequately summarized by a tree. This study investigates ways to describe their evolutionary history and proposes a method giving a partial reconstruction of this history. Multigene families, viruses, and alleles from within populations experience recombinations/gene conversions, so the questions studied here are relevant for a large body of data and the suggested solutions should be very practical. The method employed was implemented in a program, RecPars, written in C and was used to analyze nine retroviruses.
Keywords
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