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A method for the determination of perfluorooctanoic acid in blood and other biological samples

Analytical BiochemistryPublished 1 January 1980
Jon Belisle, Donald F. Hagen
Citations62
SJR quartileQ3
SJR score0.50
SNIP0.63

TL;DR

A method is presented for the analysis of perfluorooctanoic acid in plasma, urine, and liver tissue based on conversion of the acid to its methyl ester followed by separation and quantitation by gas chromatography.

Abstract

It has been suggested that perfluorooctanoic acid occurs in human plasma; however, no method of analysis for this compound in biological samples has been published to date. A method is presented for the analysis of perfluorooctanoic acid in plasma, urine, and liver tissue based on conversion of the acid to its methyl ester followed by separation and quantitation by gas chromatography.

Keywords

MedicineEnvironmental Science