Electrophysiological studies on human pain perception
Clinical NeurophysiologyPublished 13 January 2005
Ryusuke Kakigi, Koji Inui, Yohei Tamura
Citations142
SJR quartileQ1
SJR score1.33
SNIP1.38
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TL;DR
The new method, epidermal stimulation (ES), which is useful for recording brain activities by the signals ascending through A delta fibers, is introduced, which will probably be used for evaluation of continuous tonic pain such as cancer pain, which evoked response studies cannot evaluate.
Abstract
One promising approach in the near future is to analyze the change of a frequency band. This method will probably be used for evaluation of continuous tonic pain such as cancer pain, which evoked response studies cannot evaluate.
Keywords
MedicineNeuroscience
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Patients with therapy-resistant chronic pain syndromes were treated with rTMS of the corresponding motor cortex area for 20 min and some of the patients had an analgesic effect, but the difference between active and sham stimulation did not reach a level of significance.
Clinical NeurophysiologySources of cortical responses to painful CO2 laser skin stimulation of the hand and foot in the human brain
128 Citations2000Massimiliano Valeriani, Domenico Restuccia +4 more
The dipolar model previously proposed for the hand stimulation LEPs can also satisfactorily explain the LEP distribution obtained after foot stimulation and showed that the co-ordinates of the two earliest activated dipoles were compatible with source locations in the upper bank of the Sylvian fissure on both sides.
Electroencephalography and Clinical Neurophysiology/Evoked Potentials SectionLaser-evoked potentials: exogenous and endogenous components
127 Citations1996Ralf Siedenberg, Rolf‐Detlef Treede
The LEP of targets, frequent non-targets and during distraction was dominated by a single large positivity, which was task-dependent and increased the more attention the subject payed to the laser stimuli.
NeurosurgeryTranscranial Magnetic Coil Stimulation of Motor Cortex in Patients with Central Pain
126 Citations1995Keisuke Migita, Tohru Uozumi +2 more
Two patients with deafferentation pain secondary to central nervous system lesions who were evaluated by noninvasive magnetic coil stimulation of the motor cortex followed by electrical motor cortex stimulation with epidural electrode array implantation gave relief from pain.
Brain Research ReviewsThe sensory innervation of primate facial skin. I. Hairy skin
125 Citations1983Bryce L. Munger, Zdeněk Halata
The present study analyzes the variety of sensory nerve terminals present in the hairy skin of the monkey face and finds free nerve endings (FNE's) have been found in the connective tissue capsule of primate sinus and hemisinus hairs and in the same site in guard and vellus hairs.
BrainPAIN-RELATED SOMATOSENSORY EVOKED POTENTIALS IN SYRINGOMYELIA
121 Citations1991Ryusuke Kakigi, Hiroshi Shibasaki +5 more
Pain SEPs combined with electric SEPs appear to be extremely useful for investigating physiological function in the sensory pathways in patients who show 'dissociated sensory loss' such as in syringomyelia.
PainThe P300 in pain evoked potentials
118 Citations1996Ruth Zaslansky, Elliot Sprecher +3 more
It is suggested that the laser EP contains a definite non‐modality‐specific P300 component, and is not a pure neurophysiological correlate of pain intensity.
Journal of Clinical NeurophysiologyPain-Related Somatosensory Evoked Potentials
117 Citations2000Ryusuke Kakigi, Shoko Watanabe +1 more
Combining the study of pain SSEP(L) and conventional S SEP is useful to detect physiologic abnormalities, and sometimes subclinical abnormalities, of patients with peripheral and central nervous system lesions.
PainEffects of 1-Hz repetitive transcranial magnetic stimulation on acute pain induced by capsaicin
116 Citations2003Yoshihiro Tamura, Shingo Okabe +6 more
It is concluded that rTMS over M1 should have beneficial effects on acute pain, and its effects must be caused by functional changes of MPFC and caudal ACC.
Muscle & NerveEstimation of conduction velocity of Aδ fibers in humans
115 Citations1991Ryusuke Kakigi, Chiyoko Endo +3 more
Conduction velocity of Aδ fibers of the human peripheral nerves was measured by using pain‐related somatosensory evoked potentials following CO2 laser stimulation to investigate physiological functions of the small diameter fibers mediating pain‐temperature sensations.
Muscle & NerveCO<sub>2</sub> laser‐induced pain‐related somatosensory evoked potentials in peripheral neuropathies: Correlation between electrophysiological and histopathological findings
113 Citations1991Ryusuke Kakigi, Hiroshi Shibasaki +11 more
The pain SEP is the only one noninvasive and objective method currently available to investigate a physiological condition of the sensory pathway responsible for pain sense, and is especially useful when combined with the conventional electric SEPs.
Electroencephalography and Clinical NeurophysiologyPrincipal component analysis of pain-related cerebral potentials to mechanical and electrical stimulation in man
113 Citations1982B. Bromm, E. Scharein
ERP wave form was shown to depend upon the amount of alpha waves in the prestimulus EEG, and PCA applied to disjunctive subsets of ERPs yielded practically identical sets of PCs, such that no specific ERP component emerged when pain was reported.
Neuroscience LettersNeuromagnetic localization of cortical activity evoked by painful dental stimulation in man
112 Citations1983Riitta Hari, E. Kaukoranta +3 more
Cerebral magnetic fields evoked by painful dental stimulation indicate a current source at the upper bank of the anterior Sylvian Fissure, corresponding to the anterior end of the secondary somatosensory cortex, which suggests cortical representation of tooth pulp in man.
Experimental Brain ResearchAspirin analgesia evaluated by event-related potentials in man: Possible central action in brain
109 Citations1980A. C. N. CHEN, C. Richard Chapman
In this study, possible brain effects of 975 mg aspirin in man are demonstrated and it is postulated that aspirin may act centrally in pain processing.
International Journal of NeurosciencePain Related Cerebral Potentials: Late and Ultralate Components
107 Citations1987B. Bromm, Rolf‐Detlef Treede
Clinical application of CO2 laser EPs promises to nonivasively assess A delta- and C-fibre function and the filtered ultralate waveforms look very similar to the late EP components.
PainResponses of the supra-sylvian (SII) cortex in humans to painful and innocuous stimuli
106 Citations2001Maud Frot, Luís García‐Larrea +2 more
The intrinsic characteristics and localization of nociceptive CO2 laser evoked potential (LEP) and non‐nocICEptive electrical EP (SEP) sources recorded by deep electrodes directly implanted in the supra‐sylvian cortex of 15 epileptic patients are compared and the SII cortex is defined as a cortical integration area of non‐NOCiceptive and noc iceptive inputs.
Journal of NeurophysiologyDipole Source Analysis of Laser-Evoked Subdural Potentials Recorded From Parasylvian Cortex in Humans
105 Citations2003Hagen Vogel, John D. Port +4 more
The findings suggest that the nociceptive area in human parasylvian cortex that is activated most rapidly by noxious heat pulses may be separate from the tactile SII area.
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