Androgen receptor abnormality in X‐linked spinal and bulbar muscular atrophy
NeurologyPublished 1 September 1992
Tetsuya Matsuura, Takayoshi Demura, Y Aimoto, Toshiki Mizuno, Fumio Moriwaka, K Tashiro
Citations33
SJR quartileQ1
SJR score2.40
SNIP1.82
Generate an AI Snapshot to get a quick, structured summary of this paper.
Study Snapshot
ObjectiveStudy objective
MethodsResearch methodology
PopulationPopulation studied
Sample sizeSample sizes
OutcomesStudy outcomes here
ResultsStudy results comes here
LimitationsResearch study limitations comes here
A concise AI-generated summary of the paper will appear here once you click Generate AI Snapshot.
TL;DR
It is proposed that AR abnormality is the cause of X-linked spinal and bulbar muscular atrophy, and was unable to find androgen receptor (AR) in the scrota) skin of three patients with SBMA.
Abstract
X-linked spinal and bulbar muscular atrophy (SBMA) is usually associated with feminization and hypogonadism. We were unable to find androgen receptor (AR) in the scrotal skin of three patients with SBMA, and propose that AR abnormality is the cause of the disease.
Keywords
MedicineNeuroscienceBiochemistry, Genetics and Molecular Biology