Effects of Diethylstilbestrol on Feral House Mouse (Mus musculus L.) Population Dynamics Under Experimental Field Conditions
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TL;DR
Diethylstilbestrol (DES), a synthetic estrogen analogous to estradiol, represents an antifertility agent that might be employed in the control of mammalian populations functioning in natural ecosystems.
Abstract
Numerous studies have been carried out concerning the effect of estrogenic substances upon mammalian reproduction (e.g. Bennetts, Underwood & Shier 1946; Leavitt & Wright 1963; Negus & Pinter 1966). Many of these estrogenic effects have been summarized by Samuel (1967). Synthetic estrogens have been shown to produce both stimulatory and inhibitory effects upon reproduction (Bradbury 1947). Diethylstilbestrol (DES), a synthetic estrogen analogous to estradiol, represents an antifertility agent that might be employed in the control of mammalian populations functioning in natural ecosystems. DES has been employed to control mammalian reproduction under both penned (Shackelford & Cochrane 1962, Linhart & Enders 1964) and field conditions (Balser 1964). No studies have been carried out regarding the effects of DES upon feral house mouse (Mus musculus L.) population dynamics under natural environmental conditions. This study was designed to evaluate the effects of DES upon feral house mouse populations functioning within experimental ecosystems.