Antigonadotropic activity in a melatonin-free extract of human pineal glands
Life SciencesPublished 1 December 1971
Mary J. Matthews, Bryant Benson, Alvin E. Rodin
Citations13
SJR quartileQ1
SJR score1.31
SNIP1.07
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TL;DR
A melatonin-free fraction of an aqueous extract of human pineal glands, isolated on Sephadex G-25, was found to possess similar antigonadotropic activity.
Abstract
In previous studies melatonin-free, aqueous extracts of bovine pineal glands were shown to partially block compensatory ovarian hypertrophy in mice. In this study a melatonin-free fraction of an aqueous extract of human pineal glands, isolated on Sephadex G-25, was found to possess similar antigonadotropic activity. Human cerebral extract treated in the same manner did not produce this effect.
Keywords
Neuroscience
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