L-Tryptophan in Mania
Archives of General PsychiatryPublished 1 January 1974
Arthur J. Prange
Citations275
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TL;DR
Five manic patients were treated with chlorpromazine hydrochloride, then with L-tryptophan, and five with LTP first, then CPZ, in a double-blind, placebo-controlled crossover study, finding LTP was slightly superior to CPZ in all regards.
Abstract
Five manic patients were treated with chlorpromazine hydrochloride (CPZ), then with L-tryptophan (LTP), and five with LTP first, then CPZ, in a double-blind, placebo-controlled crossover study. LTP was slightly superior to CPZ in all regards. Mania and depression may be linked by a central indoleamine deficit.
Keywords
Medicine
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