The Prefrontal Cortex and Temporal Integration
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TL;DR
It is shown that the associative cortex of the frontal lobe, commonly termed the prefrontal cortex, undergoes considerable expansion in the course of evolution, and reaches its greatest development in the human brain, constituting nearly one-third of the neocortex.
Abstract
The associative cortex of the frontal lobe, commonly termed the prefrontal cortex, undergoes considerable expansion in the course of evolution. It reaches its greatest development in the human brain, constituting nearly one-third of the neocortex. Its phylogenetic expansion outstrips that of other cortical regions and also that of the mediodorsal (MD) nucleus of the thalamus, a nucleus so heavily and distinctly projecting to the prefrontal cortex that the latter is conventionally defined as the cortical territory of MD projection.
