Waist circumference vs body mass index for prediction of disease risk in postmenopausal women
International Journal of ObesityPublished 1 August 2001
Rachael E. Van Pelt, EM Evans, KB Schechtman, AA Ehsani, WM Kohrt
Citations82
SJR quartileQ1
SJR score1.59
SNIP1.33
Generate an AI Snapshot to get a quick, structured summary of this paper.
Study Snapshot
ObjectiveStudy objective
MethodsResearch methodology
PopulationPopulation studied
Sample sizeSample sizes
OutcomesStudy outcomes here
ResultsStudy results comes here
LimitationsResearch study limitations comes here
A concise AI-generated summary of the paper will appear here once you click Generate AI Snapshot.
TL;DR
Waist circumference, an easily obtained index of central adiposity, is a more sensitive measure of relative disease risk than is BMI in middle-aged and older women, particularly in normal-weight individuals.
Abstract
Waist circumference, an easily obtained index of central adiposity, is a more sensitive measure of relative disease risk than is BMI in middle-aged and older women, particularly in normal-weight individuals.
Keywords
Medicine
Clinical ChemistryEstimation of the Concentration of Low-Density Lipoprotein Cholesterol in Plasma, Without Use of the Preparative Ultracentrifuge
32,475 Citations1972William T. Friedewald, Robert I. Levy +1 more
A method for estimating the cholesterol content of the serum low-density lipoprotein fraction (Sf0-20) is presented and comparison of this suggested procedure with the more direct procedure, in which the ultracentrifuge is used, yielded correlation coefficients of .94 to .99.
Clinical ChemistryDextran sulfate-Mg2+ precipitation procedure for quantitation of high-density-lipoprotein cholesterol.
2,182 Citations1982G. Russell Warnick, J Benderson +1 more
The American Journal of CardiologyWaist circumference and abdominal sagittal diameter: Best simple anthropometric indexes of abdominal visceral adipose tissue accumulation and related cardiovascular risk in men and women
2,077 Citations1994Marie‐Christine Pouliot, Jean‐Pierre Després +6 more
It is suggested from data that waist circumference values above approximately 100 cm, or abdominal sagittal diameter values > 25 cm are most likely to be associated with potentially "atherogenic" metabolic disturbances.
New England Journal of MedicineBody Weight and Mortality among Women
1,989 Citations1995JoAnn E. Manson, Walter C. Willett +6 more
New England Journal of MedicineThe Effect of Age on the Association between Body-Mass Index and Mortality
1,628 Citations1998June Stevens, Jianwen Cai +4 more
Excess body weight increases the risk of death from any cause and from cardiovascular disease in adults between 30 and 74 years of age and the relative risk associated with greater body weight is higher among younger subjects.
JAMAAbdominal Adiposity and Coronary Heart Disease in Women
1,225 Citations1998Kathryn M. Rexrode
The WHR and waist circumference are independently associated with risk ofCHD in women and were independently strongly associated with increased risk of CHD also among women with a BMI of 25 kg/m2 or less.
DiabetesThe Influence of Body Fat Distribution on the Incidence of Diabetes Mellitus: 13.5 Years of Follow-up of the Participants in the Study of Men Born in 1913
984 Citations1985L.‐O. Ohlson, B. Larsson +6 more
Results from a prospective study strongly support previous cross-sectional findings indicating that not only the degree of obesity but also the localization of fat is a risk factor for diabetes.
American Journal of Clinical NutritionSex- and menopause-associated changes in body-fat distribution
737 Citations1992CJ Ley, Belinda Lees +1 more
DEXA measurements clearly demonstrated that sex differences in total fat mass were opposite those of android fat, and that marked menopausal changes in fat mass and its distribution existed, and suggest that DEXA measurements of fat distribution may be useful for studies related to obesity-associated disease risk.
JAMAEffects of Hormone Replacement Therapy on Endometrial Histology in Postmenopausal Women
595 Citations1996Howard L. Judd
Combining CEE with cyclic or continuous MPA or cyclic MP protected the endometrium from hyperplastic changes associated with estrogen-only therapy.
JAMABody Fat Distribution and 5-Year Risk of Death in Older Women
590 Citations1993A.R. Folsom
Waist/hip circumference ratio is a better marker than body mass index of risk of death in older women and should be measured as part of routine surveillance and risk monitoring in medical practice.
Annals of Internal MedicineChanges in Energy Balance and Body Composition at Menopause: A Controlled Longitudinal Study
518 Citations1995Éric T. Poehlman, Michael J. Toth +1 more
Compared longitudinal changes in resting metabolic rate, body composition, and physical activity in a cohort of healthy premenopausal women who experienced menopause with changes in these variables in a cohorts of women who remained pre menopausal.
The LancetImpairment of health and quality of life in people with large waist circumference
505 Citations1998MEJ Lean, Thang S. Han +1 more
Above action level 2, men and women were at twice the risk of difficulties in everyday activities, women were 1.5 times more likely to have low back pain or symptoms of intervertebral disc herniation, with secondary problems including hindrance to daily activities.
NutritionBody fat distribution, insulin resistance, and metabolic diseases
467 Citations1997Per Björntorp
These findings strongly support the interpretation that a stress reaction activating the HPA axis is involved also in the human syndrome, suggesting that the pathogenesis of abdominal preponderance of body fat and its endocrine, anthropometric and metabolic abnormalities are indeed consequences of the endocrine abnormalities identified.
Archives of Internal MedicineWeight Gain at the Time of Menopause
389 Citations1991Rena R. Wing
Weight gain is a common occurrence for women at the time of menopause and is related to the changes in coronary heart disease risk factors observed during this period, and efforts to lose weight or to prevent weight gain may help to mitigate the worsening in coronaryHeart disease risk Factors in middle-aged women.
Archives of Internal MedicineRisk Factors That Attenuate the Female Coronary Disease Advantage
366 Citations1995W B Kannel
Coronary disease is not a minor problem in women, and women should take vigorous preventive measures, including particular attention to glucose tolerance and blood lipid levels and a greater sense of urgency when hypertension progresses to left ventricular hypertrophy.
The Journal of Clinical Endocrinology & MetabolismBody Weight, Body Fat Distribution, and Hormonal Replacement Therapy in Early Postmenopausal Women
313 Citations1997Marco Gambacciani, Massimo Ciaponi +5 more
The present results suggest that HRT can counteract at least in part the postmenopausal increase in body weight and body fat and prevent central body fat distribution after menopause.
Obesity ResearchThe Insulin Resistance—Dyslipidemic Syndrome of Visceral Obesity: Effect on Patients' Risk
264 Citations1998Jean‐Pierre Després
The high prevalence of visceral obesity in sedentary adult men and postmenopausal women is such that it may represent the most prevalent cause of atherogenic dyslipidemic states associated with CHD in the population.
Journal of Internal MedicineNarrow hips and broad waist circumferences independently contribute to increased risk of non‐insulin‐dependent diabetes mellitus
211 Citations1997Jacob C. Seidell, Thang S. Han +2 more
Narrow hips and broad waist circumferences independently contribute to increased risk of non‐insulin‐dependent diabetes mellitus.
The Journal of Clinical Endocrinology & MetabolismEffect of Postmenopausal Hormone Therapy on Body Weight and Waist and Hip Girths<sup>1</sup>
210 Citations1997Mark A. Espeland, Marcia L. Stefanick +5 more
The impact of hormone therapy on weight gain was similar among subgroups, except for those defined by baseline smoking status and physical activity level at home, which significantly affected the observed overall relationships between estrogen and changes in girth.
PubMedBody composition of healthy sedentary and trained, young and older men and women.
155 Citations1992Wendy M. Kohrt, M. T. Malley +2 more
PubMedReproductive history in relation to relative weight and fat distribution.
153 Citations1996Cecilia Björkelund, Lauren Lissner +3 more
Journal of GerontologyExercise Training Improves Fat Distribution Patterns in 60-to 70-year-old Men and Women
125 Citations1992Wendy M. Kohrt, Kathleen A. Obert +1 more
It is indicated that endurance exercise training can favorably modify the abdominal fat distribution profile that is typical of older men and women in the United States and thus, perhaps, reduce the risk of the diseases associated with abdominal obesity.
Diabetes CareEffects of postmenopausal hormone replacement therapy on central abdominal fat, glycemic control, lipid metabolism, and vascular factors in type 2 diabetes: a prospective study.
121 Citations1999Katherine Samaras, Christopher S. Hayward +3 more
Postmenopausal HRT in these overweight women with type 2 diabetes was associated with a reduction in central adiposity and improvement in lipid metabolism and glycemic control without deterioration in weight status or cardiovascular parameters measured.
Medicine & Science in Sports & ExerciseBody composition of healthy sedentary and trained, young and older men and women
111 Citations1992Wendy M. Kohrt, MARY T. MALLEY +2 more
People who exercise regularly appear to accumulate less adipose tissue in upper, central body regions as they get older, potentially reducing the risk for the metabolic disorders associated with upper body obesity.
Journal of Applied PhysiologyHRT preserves increases in bone mineral density and reductions in body fat after a supervised exercise program
109 Citations1998Wendy M. Kohrt, Ali A. Ehsani +1 more
It is suggested that HRT is an important adjunct to exercise for the prevention not only of osteoporosis but also of diseases related to abdominal obesity.
American Journal of Physiology-Endocrinology and MetabolismSmaller differences in total and regional adiposity with age in women who regularly perform endurance exercise
57 Citations1998Rachael E. Van Pelt, Kevin P. Davy +5 more
Experimental support is provided for the hypothesis that women who regularly engage in vigorous endurance exercise may not gain body weight, undergo only a modest increase in total body fat, and do not demonstrate a significant elevation in central adiposity with age.
