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Susceptibility of a reactivated memory to the effects of strychnine: A time-dependent phenomenon

Physiology & BehaviorPublished 1 January 1977
William C. Gordon
Citations68
SJR quartileQ2
SJR score0.78
SNIP0.84

TL;DR

It was demonstrated in Experiment 1 that the administration of strychnine following memory reactivation results in facilitated retention and this facilitation was shown to decrease as the interval between reactivation and the drug treatment was increased.

Abstract

It was demonstrated in Experiment 1 that the administration of strychnine following memory reactivation results in facilitated retention. Furthermore, this facilitation was shown to decrease as the interval between reactivation and the drug treatment was increased. The retrograde facilitation gradient found in Experiment 1 was shown to have a much shorter duration than the gradient produced by injecting strychnine at various intervals after original learning (Experiment 2). The possibility that reactivation and new learning initiate similar types of memory processing was discussed.

Keywords

NeurosciencePharmacology, Toxicology and Pharmaceutics