Leisure-time physical activity at midlife and the risk of dementia and Alzheimer's disease
The Lancet NeurologyPublished 5 October 2005
Suvi Rovio, Ingemar Kåreholt, Eeva‐Liisa Helkala, Matti Viitanen, Bengt Winblad, Jaakko Tuomilehto
Citations1,059
SJR quartileQ1
SJR score11.73
SNIP13.75
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TL;DR
Leisure-time physical activity at midlife at least twice a week was associated with a reduced risk of dementia and AD later in life, and the associations were more pronounced among the APOE epsilon4 carriers.
Abstract
Leisure-time physical activity at midlife is associated with a decreased risk of dementia and AD later in life. Regular physical activity may reduce the risk or delay the onset of dementia and AD, especially among genetically susceptible individuals.
Keywords
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