Pathogenesis of cachexia in cancer.A review and a hypothesis
CancerPublished 1 February 1972
Athanasios Theologides
Citations140
SJR quartileQ1
SJR score2.95
SNIP1.90
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TL;DR
The clinical features of cachexia characterized by anorexia, marked asthenia, significant loss of body fat, protein and other components, anemia, water and electrolyte abnormalities and increased basal metabolic rate and energy expenditure despite the reduced dietary intake are just the most obvious manifestations of a profound systemic derangement of the host metabolism.
Abstract
The clinical features of cachexia characterized by anorexia, marked asthenia, significant loss of body fat, protein and other components, anemia, water and electrolyte abnormalities and increased basal metabolic rate and energy expenditure despite the reduced dietary intake are just the most obvious manifestations of a profound systemic derangement of the host metabolism. A hypothesis to explain the pathogenesis of cancer cachexia is proposed.
Keywords
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