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Cytotoxin production by Campylobacter pylori strains isolated from patients with peptic ulcers and from patients with chronic gastritis only

Journal of Clinical MicrobiologyPublished 1 January 1989Open access
Natale Figura, P Guglielmetti, A Rossolini, A Barberi, Maria Grazia Cusi, R. A. Musmanno
Citations408
SJR quartileQ1
SJR score1.88
SNIP1.68
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TL;DR

A total of 66.6% of Campylobacter pylori strains isolated from patients with peptic ulcers produced a cytotoxin active against mammalian cells in vitro, which suggests that the toxic substance could be involved in the development of peptic Ulcers.

Abstract

A total of 66.6% of Campylobacter pylori strains isolated from patients with peptic ulcers produced a cytotoxin active against mammalian cells in vitro, versus 30.1% of strains isolated from patients with chronic gastritis of various degrees of severity only. This difference was statistically significant and suggests that the toxic substance could be involved in the development of peptic ulcers.

Keywords

Medicine