Incidence, prise en charge et coût des condylomes acuminés anogénitaux chez les femmes consultant leur gynécologue en France
Gynécologie Obstétrique & FertilitéPublished 1 February 2007
Joseph Monsonégo, J. Gabrielle Breugelmans, S. Bouée, A Lafuma, Stève Bénard, V. Rémy
Citations66
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TL;DR
The introduction of a quadrivalent (type 6,11,16,18) Human Papillomavirus vaccine including types responsible for 90% of genital warts could potentially substantially reduce these costs.
Abstract
The costs of treating genital warts are considerable. The introduction of a quadrivalent (type 6,11,16,18) Human Papillomavirus vaccine including types responsible for 90% of genital warts could potentially substantially reduce these costs.
Keywords
Medicine
New England Journal of MedicineEpidemiologic Classification of Human Papillomavirus Types Associated with Cervical Cancer
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JNCI Journal of the National Cancer InstitutePrevalence of Human Papillomavirus in Cervical Cancer: a Worldwide Perspective
3,434 Citations1995F. Xavier Bosch, M. Michele Manos +9 more
The results confirm the role of genitalHPVs, which are transmitted sexually, as the central etiologic factor in cervical cancer worldwide and suggest that most genital HPVs are associated with cancer, at least occasionally.
The Lancet OncologyProphylactic quadrivalent human papillomavirus (types 6, 11, 16, and 18) L1 virus-like particle vaccine in young women: a randomised double-blind placebo-controlled multicentre phase II efficacy trial
1,580 Citations2005Luisa L. Villa, Ronaldo Lúcio Rangel Costa +27 more
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JNCI Journal of the National Cancer InstitutePapillomaviruses Causing Cancer: Evasion From Host-Cell Control in Early Events in Carcinogenesis
1,317 Citations2000H. zur Hausen
Modifications in host-cell genes, most likely engaged in the control of HPV gene expression in proliferating cells, emerge as important events in HPV-mediated carcinogenesis.
The American Journal of MedicineEpidemiology of Genital Human Papillomavirus Infection
1,119 Citations1997Laura A. Koutsky
Strong epidemiologic and molecular data link HPV infection to cervical and other anogenital cancers, and the types of HPV most commonly detected in cancers are HPV-16 and HPV-18.
Cancer Epidemiology Biomarkers & PreventionHuman Papillomavirus Genotype Distribution in Low-Grade Cervical Lesions: Comparison by Geographic Region and with Cervical Cancer
536 Citations2005Gary M. Clifford, Rashida K. Rana +4 more
HPV genotyping may have the potential to improve the effectiveness of screening programs and to reduce overtreatment in low-grade squamous intraepithelial lesions associated with certain human papillomavirus genotypes, which may preferentially progress to cervical cancer.
International Journal of CancerHuman papillomavirus—the most significant risk determinant of cervical intraepithelial neoplasia
206 Citations1996Susanne K. Kjær, Adriaan J. C. van den Brule +6 more
Cervical HPV infection was by far the most significant risk factor for cervical squamous intraepithelial lesions and the importance of the previously identified epidemiological risk factors for cervical neoplasia was also demonstrated.
International Journal of STD & AIDSAn international survey of patients with genital warts: perceptions regarding treatment and impact on lifestyle
176 Citations1998R D Maw, Michael Reitano +1 more
Country-specific attitudes and perceptions of patients with genital warts in Canada, France, Germany, the UK, and the USA are determined and a better understanding of the psychosexual aspect of the disease by health-care providers is pivotal to effective disease management and patient counselling.
PubMedManagement of anogenital warts (condylomata acuminata).
106 Citations2001Geo von Krogh
Epidemiology and pathogenesis * Acquisition rates correlate with the number of lifetime sexual partners, being > 50% in people with > 5 partners, and being inversely correlated with condom use.
Sexually Transmitted DiseasesTreatment of External Genital Warts in Men Using 5% Imiquimod Cream Applied Three Times a Week, Once Daily, Twice Daily, or Three Times a Day
71 Citations2001Kenneth H. Fife, Alex Ferenczy +4 more
In this study, the optimal dosage regimen was the approved three times a week regimen, and there was a significant increase in the incidence and severity of local skin reactions including erythema, vesicle formation, ulceration, and excoriation as the dosing frequency increased.
Journal of the American Academy of DermatologyCondylomata acuminata (genital warts)
67 Citations1987Tsu‐Yi Chuang
It is strongly recommended that patients should be followed up periodically for early detection of neoplasia and the potential for malignant transformation of condyloma acuminatum.
Sexually Transmitted InfectionsEpidemiology of genital warts in England and Wales: 1971 to 1994.
61 Citations1997Ian Simms, Christopher K. Fairley
Rates of genital warts have risen substantially over the past 25 years and if these are a reflection of changes in sexual behaviour then the rise since 1992 is of considerable concern particularly for the incidence of cervical cancer in the coming decades.
Sexually Transmitted DiseasesPhysical and Psychological Effects of Anogenital Warts on Female Patients
43 Citations1993Göran Persson, LARS GOSTA DAHLOF +1 more
There were significant differences in experiences of pleasantness, activation, and social orientation, which suggest a conspicuous emotional effect of the disease.
Gynécologie Obstétrique & FertilitéPrévention du cancer du col utérin : enjeux et perspectives de la vaccination antipapillomavirus
33 Citations2006Joseph Monsonégo
Three large phases prophylactic HPV VLP trials are now in progress and will form the basis for licensing of candidate vaccines in 2006, and HPV vaccination targeting young female adolescents, aged 11 to 16 years, with a catch-up of those aged 17-25 years, would be a strategy to be addressed.
PubMed[Dermatology in private practice in France in 2000].
33 Citations2002Esther Lukasiewicz, José Martel +2 more
American Journal of Clinical PathologyLSIL Biopsies After HSIL Smears: Correlation With High-Risk HPV and Greater Risk of HSIL on Follow-Up
28 Citations1999Felix M. Brown, William C. Faquin +3 more
Cases of HSIL cytology/LSIL histology represent a group distinct from unselected LSILs by virtue of their higher prevalence of high-risk HPV types and, therefore, warrant closer clinical follow-up.
PubMed[Incidence and management of condylomata acuminata by French general physicians].
27 Citations2002Esther Lukasiewicz, S. Aractingi +1 more
The incidence of external condylomata acuminata in France is similar to those estimated in others developed countries.
PubMed[A model-based comparison of cost effectiveness of imiquimod versus podophyllotoxin for the treatment of external anogenital warts in France].
14 Citations2004A Lafuma, Joseph Monsonégo +2 more
Imiquimod, because of its greater initial efficacy, is at least as cost-effective as podophyllotoxin the treatment of external genital warts and laser therapy in the case of failure or relapse.
Gynécologie Obstétrique & FertilitéVaccins prophylactiques antipapillomavirus : enjeux et perspectives
12 Citations2006Sébastien Hantz, Sophie Alain +1 more
La strategie vaccinale definie a ce jour cible les jeunes filles preadolescentes and adolescentes (11–13 ans) avant les premiers rapports sexuels mais certaines questions sont encore en suspens concernant le prescripteur, the personne qui vaccinera and the duree de protection conferee par le vaccin.
PubMedTransmission of HPV.
10 Citations2003Sarah M. Giles
Human papillomavirus infection in women, relating this infection to various risk factors, including number of previous sexual partners, is described.
PubMed[Management of external genital warts by dermatologists: a French survey].
10 Citations2002E. Mahé, V Descamps +2 more
The study points out the lack of global management (loco-regional, partner, and STD evaluation) of the disease by dermatologists.