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Movement Disorders Associated With the Serotonin Selective Reuptake Inhibitors

The Journal of Clinical PsychiatryPublished 15 October 1996
Raphael J. Leo
Citations360
SJR quartileQ1
SJR score1.49
SNIP1.38

TL;DR

SSRI-induced extrapyramidal symptoms are probably related to agonism of serotonergic input to dopaminergic pathways within the CNS and several patient-dependent and pharmacokinetic variables may determine the likelihood that EPS will emerge.

Abstract

SSRI-induced EPS are probably related to agonism of serotonergic input to dopaminergic pathways within the CNS. Several patient-dependent and pharmacokinetic variables may determine the likelihood that EPS will emerge. Although these side effects are infrequent, clinicians should be alert to the possibility of their occurrence.

Keywords

Medicine