Capacitive and ionic currents in BLM from phosphatidic acid in Ca2+-induced phase transition

Biochemical and Biophysical Research CommunicationsPublished 1 December 1985

V. F. Antonov, Elena V. Shevchenko, E.T. Kozhomkulov, A. A. Molnar, E. Yu. Smirnova

DOI10.1016/0006-291x(85)91249-5

Source URL

Citations17

SJR quartileQ2

SJR score0.75

SNIP0.56

TL;DR

The phase transition in the Ca2+-induced BLM is accompanied by the initial capacitive current followed by the occurrence of single ionic channels, which results in the development of electric current with time in a bilayer lipid membrane.

Abstract

The development of electric current with time in a bilayer lipid membrane (BLM) formed from dipalmitoylphosphatidic acid on introducing Ca2+ ions into the medium was studied at constant temperature and pH. The phase transition in the Ca2+-induced BLM is accompanied by the initial capacitive current followed by the occurrence of single ionic channels. The amount of transported charges in the capacitive current is 5 C/ microF. The conductivity of the single ionic channels ranges from 50 to 100 pSm.

Keywords

ChemistryBiochemistry, Genetics and Molecular BiologyEngineering

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