Rapid Control of Psychotic Excitement States with Intramuscular Haloperidol
American Journal of PsychiatryPublished 1 October 1973
FRANCINE SANGIOVANNI, Michael Alan Taylor, Richard Abrams, Pedro Gaztanaga
Citations42
SJR quartileQ1
SJR score5.27
SNIP3.68
Generate an AI Snapshot to get a quick, structured summary of this paper.
Study Snapshot
ObjectiveStudy objective
MethodsResearch methodology
PopulationPopulation studied
Sample sizeSample sizes
OutcomesStudy outcomes here
ResultsStudy results comes here
LimitationsResearch study limitations comes here
A concise AI-generated summary of the paper will appear here once you click Generate AI Snapshot.
TL;DR
The preliminary results suggest that intramuscular haloperidol in doses up to 60 mg.
Abstract
The authors conducted an open clinical trial of high doses of parenteral haloperidol in the treatment of 40 acutely excited psychotic inpatients. Their preliminary results suggest that intramuscular haloperidol in doses up to 60 mg. a day is safe, effective, and well tolerated in the management of such patients. Adverse reactions, which were infrequent, included extrapyramidal symptoms, lethargy, and, in one patient, transient hypotension.
Keywords
Medicine
Archives of General PsychiatryVery High Dosage Fluphenazine for Nonchronic Treatment-Refractory Patients
40 Citations1971Arthur Rifkin
Seven schizophrenics and three patients with severe character disorders who were refractory to usual psychotropic medication were treated with fluphenazine hydrochloride for two to nine months, confirming the French observation that at low dosage the predominant side effects are extrapyramidal while at high dose, the most frequent side effect is mild sedation.
American Journal of PsychiatryComparison of Injectable Haloperidol and Chlorpromazine
24 Citations1972Robert M. Ritter, David E. Davidson +1 more
While both groups improved, haloperidol effected a significantly greater improvement in patients 40 years of age or older than did chlorpromazine.