login

Adaptation of the rat liver tyrosine-α-ketoglutarate transaminase

Biochimica et Biophysica ActaPublished 1 October 1957
Edmund C.C. Lin, W. Eugene Knox
Citations421

TL;DR

Adaptive increase of the tyrosine-α-ketoglutarate transaminase occurred in the livers of rats following injections of tyrosines or of hydrocortisone, and analysis showed that hydroc Cortisone itself was a sufficient inducing stimulus.

Abstract

Adaptive increase of the tyrosine-α-ketoglutarate transaminase occurred in the livers of rats following injections of tyrosine or of hydrocortisone. The increases were as great as 10-fold and occurred in 5 hours. Analysis showed that hydrocortisone itself was a sufficient inducing stimulus. Tyrosine was an effective inducing stimulus only if the adrenal glands or hydrocortisone also were present.

Keywords

Immunology and MicrobiologyBiochemistry, Genetics and Molecular Biology