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Urinary catecholamines: Comparison between HPLC with electrochemical detection and fluorophotometric assay

Pharmacology Biochemistry and BehaviorPublished 1 October 1988
Ulf Lundberg, Lars Holmberg, Marianne Frankenhaeuser
Citations15
SJR quartileQ1
SJR score0.95
SNIP0.81

TL;DR

It was concluded that fluorometric assays provide as valid and sensitive indices of stress-induced changes in catecholamine excretion in humans as HPLC.

Abstract

Comparisons between catecholamines determined by HPLC (with electrochemical detection) and fluorometry in urine samples from healthy adults and children, respectively, showed high correlations. In agreement with greater specificity for HPLC, mean values were higher for the fluorometric assay. However, it was concluded that fluorometric assays provide as valid and sensitive indices of stress-induced changes in catecholamine excretion in humans as HPLC.

Keywords

MedicineNeuroscience